ReviewNature reviews. Urology2015
The elementome of calcium-based urinary stones and its role in urolithiasis.
Review in Nature reviews. Urology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 74 citations in OpenAlex.
- Steroid hormones and nephrolithiasis: regulation of urine components metabolism and inflammation.Biology of sex differences · 2026Review
- Elemental composition analysis of calcium-based urinary stones via laser-induced breakdown spectroscopy for enhanced clinical insights.Scientific reports · 2025Article
- Symptomatic urinary stone disease in Kazakhstan: hospitalization trends from the national electronic healthcare system (2014-2021).Urolithiasis · 2025Article
- Disruptions in Renal Stone Management during the COVID-19 Pandemic: a Retrospective Single-Center Study.Maedica · 2025Article
- Risk factors of urolithiasis: A hospital-based retrospective study.Journal of family medicine and primary care · 2024Article
- The key role of major and trace elements in the formation of five common urinary stones.BMC urology · 2024Article
- Assessment of the incidence and risk factors of postoperative urosepsis in patients undergoing ureteroscopic lithotripsy.Central European journal of urology · 2024Article
- A Simple Laser-Induced Breakdown Spectroscopy Method for Quantification and Classification of Edible Sea Salts Assisted by Surface-Hydrophilicity-Enhanced Silicon Wafer Substrates.Sensors (Basel, Switzerland) · 2023Article
- A simple assessment of the effect of strontium on the urinary excretion of calcium in Sprague Dawley rats.Urolithiasis · 2023Article
- Did the COVID-19 Pandemic Restrict Access to Emergency Urological Services: Assessment of Reorganisation Effectiveness for Hospital Treatment.International journal of environmental research and public health · 2023Article
- Prevalence and Risk Factors of Urolithiasis Among the Population of Hail, Saudi Arabia.Cureus · 2022Article
- Prediction of the composition of urinary stones using deep learning.Investigative and clinical urology · 2022Article
- Bladder stone caused by misplaced intrauterine contraceptive device: a case report.The Pan African medical journal · 2022Article
- Spectroscopic Characterization of Urinary Stones Richening with Calcium Oxalate.Biological trace element research · 2021Article
- Study of risk factor of urinary calculi according to the association between stone composition with urine component.Scientific reports · 2021Article
- Comparative analysis ofHeliyon · 2021Article
- Analysis of stones formed in the human gall bladder and kidney using advanced spectroscopic techniques.Biophysical reviews · 2020Review
- Electron probe micro-analysis reveals the complexity of mineral deposition mechanisms in urinary stones.Urolithiasis · 2019Article
- A Short Review on the Relationships Between Nephrolithiasis and Myocardial Infarction.Galen medical journal · 2019Review
- The relationship between kidney stones and dietary habits.Research and reports in urology · 2019Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Urolithiasis affects around 10% of the US population with an increasing rate of prevalence, recurrence and penetrance. The causes for the formation of most urinary calculi remain poorly understood, but obtaining the chemical composition of these stones might help identify key aspects of this process and new targets for treatment. The majority of urinary stones are composed of calcium that is complexed in a crystalline matrix with organic and inorganic components. Surprisingly, mitigation of urolithiasis risk by altering calcium homeostasis has not been very effective. Thus, studies to identify other therapeutic stone-specific targets, using proteomics, metabolomics and microscopy techniques, have been conducted, revealing a high level of complexity. The data suggest that numerous metals other than calcium and many nonmetals are present within calculi at measurable levels and several have distinct distribution patterns. Manipulation of the levels of some of these elemental components of calcium-based stones has resulted in clinically beneficial changes in stone chemistry and rate of stone formation. The elementome--the full spectrum of elemental content--of calcium-based urinary calculi is emerging as a new concept in stone research that continues to provide important insights for improved understanding and prevention of urinary stone disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.