ArticleJournal of neurophysiology2015
Counting on dis-inhibition: a circuit motif for interval counting and selectivity in the anuran auditory system.
Article in Journal of neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- A computational theory of short-term synaptic plasticity: synapses learn to tell time.Research square · 2026Article
- Long-interval neurons are selective for slower pulse rates in chorus frogs that are sympatric versus allopatric with congeneric heterospecifics.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Article
- Evidence that interval-counting neurons play a critical role in call recognition by Cope's gray treefrogs.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Article
- How auditory neurons count temporal intervals and decode information.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Ascending neurons convey behavioral state to integrative sensory and action selection brain regions.Nature neuroscience · 2023Article
- A biophysical counting mechanism for keeping time.Biological cybernetics · 2022Review
- Neural basis of acoustic species recognition in a cryptic species complex.The Journal of experimental biology · 2021Article
- Neurogenomic divergence during speciation by reinforcement of mating behaviors in chorus frogs (Pseudacris).BMC genomics · 2021Article
- Periodicity Pitch Perception.Frontiers in neuroscience · 2020Article
- A neuromechanistic model for rhythmic beat generation.PLoS computational biology · 2019Article
- Inhibitory Pathways for Processing the Temporal Structure of Sensory Signals in the Insect Brain.Frontiers in psychology · 2018Review
- The numerical abilities of anurans and their neural correlates: insights from neuroethological studies of acoustic communication.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Counting insects.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Information can be encoded in the temporal patterning of spikes. How the brain reads these patterns is of general importance and represents one of the greatest challenges in neuroscience. We addressed this issue in relation to temporal pattern recognition in the anuran auditory system. Many species of anurans perform mating decisions based on the temporal structure of advertisement calls. One important temporal feature is the number of sound pulses that occur with a species-specific interpulse interval. Neurons representing this pulse count have been recorded in the anuran inferior colliculus, but the mechanisms underlying their temporal selectivity are incompletely understood. Here, we construct a parsimonious model that can explain the key dynamical features of these cells with biologically plausible elements. We demonstrate that interval counting arises naturally when combining interval-selective inhibition with pulse-per-pulse excitation having both fast- and slow-conductance synapses. Interval-dependent inhibition is modeled here by a simple architecture based on known physiology of afferent nuclei. Finally, we consider simple implementations of previously proposed mechanistic explanations for these counting neurons and show that they do not account for all experimental observations. Our results demonstrate that tens of millisecond-range temporal selectivities can arise from simple connectivity motifs of inhibitory neurons, without recourse to internal clocks, spike-frequency adaptation, or appreciable short-term plasticity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.