ArticleAsian-Australasian journal of animal sciences2015
A Genome-wide Scan for Selective Sweeps in Racing Horses.
Article in Asian-Australasian journal of animal sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- Identification of Genomic Differences Resulting from Selection in Iranian Kurdish and Turkmen Horse Breeds Using Single Nucleotide Polymorphisms.Iranian journal of biotechnology · 2026Article
- The Heritability of Migration Behaviors in a Wide-Ranging Ungulate.Ecology and evolution · 2026Article
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- DCMS analysis revealed differential selection signatures in the transboundary Sahiwal cattle for major economic traits.Scientific reports · 2025Article
- Novel 61-bp Indel ofFrontiers in genetics · 2021Article
- Comparative population genomic analysis uncovers novel genomic footprints and genes associated with small body size in Chinese pony.BMC genomics · 2020Article
- Whole-Genome Signatures of Selection in Sport Horses Revealed Selection Footprints Related to Musculoskeletal System Development Processes.Animals : an open access journal from MDPI · 2019Article
- Ten years of the horse reference genome: insights into equine biology, domestication and population dynamics in the post-genome era.Animal genetics · 2019Review
- Article
- Comprehensive genome and transcriptome analyses reveal genetic relationship, selection signature, and transcriptome landscape of small-sized Korean native Jeju horse.Scientific reports · 2019Article
- Signatures of selection in the genome of Swedish warmblood horses selected for sport performance.BMC genomics · 2019Article
- The use of the SLC16A1 gene as a potential marker to predict race performance in Arabian horses.BMC genetics · 2019Article
- Selection signatures in four German warmblood horse breeds: Tracing breeding history in the modern sport horse.PloS one · 2019Article
- Article
- A genome-wide association study for harness racing success in the Norwegian-Swedish coldblooded trotter reveals genes for learning and energy metabolism.BMC genetics · 2018Article
- Analysis of cross-population differentiation between Thoroughbred and Jeju horses.Asian-Australasian journal of animal sciences · 2018Article
- Genome-Wide Signatures of Selection Reveal Genes Associated With Performance in American Quarter Horse Subpopulations.Frontiers in genetics · 2018Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Using next-generation sequencing, we conducted a genome-wide scan of selective sweeps associated with selection toward genetic improvement in Thoroughbreds. We investigated potential phenotypic consequence of putative candidate loci by candidate gene association mapping for the finishing time in 240 Thoroughbred horses. We found a significant association with the trait for Ral GApase alpha 2 (RALGAP2) that regulates a variety of cellular processes of signal trafficking. Neighboring genes around RALGAP2 included insulinoma-associated 1 (INSM1), pallid (PLDN), and Ras and Rab interactor 2 (RIN2) genes have similar roles in signal trafficking, suggesting that a co-evolving gene cluster located on the chromosome 22 is under strong artificial selection in racehorses.
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