Trial reportPloS one2015
Enhancing Cognitive Abilities with Comprehensive Training: A Large, Online, Randomized, Active-Controlled Trial.
Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
72 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- The use of commercial computerised cognitive games in older adults: a meta-analysis.Scientific reports · 2020Pooled it
- Computerised cognitive training for 12 or more weeks for maintaining cognitive function in cognitively healthy people in late life.The Cochrane database of systematic reviews · 2020Pooled it
- Computerised cognitive training for maintaining cognitive function in cognitively healthy people in late life.The Cochrane database of systematic reviews · 2019Pooled it
- Computerised cognitive training for preventing dementia in people with mild cognitive impairment.The Cochrane database of systematic reviews · 2019Pooled it
- Computerised cognitive training for maintaining cognitive function in cognitively healthy people in midlife.The Cochrane database of systematic reviews · 2019Pooled it
- Enhancing Cognitive Functioning in Healthly Older Adults: a Systematic Review of the Clinical Significance of Commercially Available Computerized Cognitive Training in Preventing Cognitive Decline.Neuropsychology review · 2017Pooled it
- Efficacy and safety of SDT-001, a dual-task digital device, in managing attention-deficit/hyperactivity disorder symptoms in children and adolescents: a phase 3, randomized, standard treatment-controlled study.Psychiatry and clinical neurosciences · 2025Trial
- Practice makes perfect, but to what end? Computerised brain training has limited cognitive benefits in healthy ageing.Psychological research · 2025Trial
- A new program for systematically enhancing cognitive reserve in healthy adults: A pilot randomized active-controlled clinical trial.PloS one · 2025Trial
- Does Sleep Moderate the Effects of Exercise Training or Complex Mental and Social Activities on Cognitive Function in Adults With Chronic Stroke? Secondary Analysis of a Randomized Trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Trial
- Randomized clinical trial on the effects of a computerized cognitive training for pediatric patients with acquired brain injury or congenital malformation.Scientific reports · 2023Trial
- Computerized Games versus Crosswords Training in Mild Cognitive Impairment.NEJM evidence · 2022Trial
- Effect of Exercise Training or Complex Mental and Social Activities on Cognitive Function in Adults With Chronic Stroke: A Randomized Clinical Trial.JAMA network open · 2022Trial
- Cognitive Training with Neurofeedback Using fNIRS Improves Cognitive Function in Older Adults.International journal of environmental research and public health · 2022Trial
- Impact of Pediatric Mobile Game Play on Healthy Eating Behavior: Randomized Controlled Trial.JMIR mHealth and uHealth · 2020Trial
- Home-based cognitive training in pediatric patients with acquired brain injury: preliminary results on efficacy of a randomized clinical trial.Scientific reports · 2020Trial
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- A yoga program for cognitive enhancement.PloS one · 2017Trial
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA variety of studies have demonstrated gains in cognitive ability following cognitive training interventions. However, other studies have not shown such gains, and questions remain regarding the efficacy of specific cognitive training interventions. Cognitive training research often involves programs made up of just one or a few exercises, targeting limited and specific cognitive endpoints. In addition, cognitive training studies typically involve small samples that may be insufficient for reliable measurement of change. Other studies have utilized training periods that were too short to generate reliable gains in cognitive performance.
methodsThe present study evaluated an online cognitive training program comprised of 49 exercises targeting a variety of cognitive capacities. The cognitive training program was compared to an active control condition in which participants completed crossword puzzles. All participants were recruited, trained, and tested online (N = 4,715 fully evaluable participants). Participants in both groups were instructed to complete one approximately 15-minute session at least 5 days per week for 10 weeks.
resultsParticipants randomly assigned to the treatment group improved significantly more on the primary outcome measure, an aggregate measure of neuropsychological performance, than did the active control group (Cohen's d effect size = 0.255; 95% confidence interval = [0.198, 0.312]). Treatment participants showed greater improvements than controls on speed of processing, short-term memory, working memory, problem solving, and fluid reasoning assessments. Participants in the treatment group also showed greater improvements on self-reported measures of cognitive functioning, particularly on those items related to concentration compared to the control group (Cohen's d = 0.249; 95% confidence interval = [0.191, 0.306]).
conclusionTaken together, these results indicate that a varied training program composed of a number of tasks targeted to different cognitive functions can show transfer to a wide range of untrained measures of cognitive performance.
trial registrationClinicalTrials.gov NCT-02367898.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.