Evidence map›Paper›PMID 26331604›Full record

ArticleCell metabolism2015

Members Only: Hypoxia-Induced Cell-Cycle Activation in Cardiomyocytes.

Arun Sharma, Sean M Wu

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell metabolism, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Arun SharmaInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
Sean M WuInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: smwu@stanford.edu.
California Institute for Regenerative Medicine · US

Funding

Induced pluripotent stem cells in the understanding and treatment of heart diseaseU01HL099776 · NHLBI · STANFORD UNIVERSITY · PI LONGAKER, MICHAEL T, WU, JOSEPH C. · 2009 to 2015
$8.2M
Enabling Technologies for Human-Machine Hybrid TissuesDP1LM012179 · NLM · STANFORD UNIVERSITY · PI WU, SEAN M · 2014 to 2018
$3.8M
NCCDPHP CDC HHS DP1 LM012179NHLBI NIH HHS U01HL099067NHLBI NIH HHS U01 HL099776NLM NIH HHS DP1 LM012179
6 · The paper itself

Abstract

A low level of cardiomyocyte turnover occurs in the adult mammalian heart, but the source of these new cells remains unknown. Kimura et al., 2015 utilized a novel hypoxia-induced fate mapping system to identify a rare population of adult cardiomyocytes undergoing cell-cycle entry and expansion in healthy adult hearts and following ischemic injury.

Indexed as

AnimalsFemaleMaleMyocardiumMyocytes, CardiacRecombinant Fusion ProteinsRecombinant Fusion ProteinsCardiomyocytehypoxiaproliferation

Identifiers

PMID26331604
OpenAlexW1877749691

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.