Cancer: Mutant p53 and chromatin regulation.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

17 citing papers in PubMed.

1. Lineage of drug discovery research on fluorinated pyrimidines: chronicle of the achievements accomplished by Professor Setsuro Fujii.International journal of clinical oncology · 2023
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2. E6-Encoded by Cancer-Causing Human Papillomavirus Interacts with Aurora Kinase A To Promote HPV-Mediated Carcinogenesis.Journal of virology · 2023
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3. Mutational Damages in Malignant Lung Tumors.Asian Pacific journal of cancer prevention : APJCP · 2023
   Article
4. Decoding the role of coiled-coil motifs in human prion-like proteins.Prion · 2021
   Review
5. Frame-shift mediated reduction of gain-of-function p53 R273H and deletion of the R273H C-terminus in breast cancer cells result in replication-stress sensitivity.Oncotarget · 2021
   Article
6. Histone Monoubiquitination in Chromatin Remodelling: Focus on the Histone H2B Interactome and Cancer.Cancers · 2020
   Review
7. Mutant p53 in colon cancer.Journal of molecular cell biology · 2019
   Review
8. Aberrant expression of ETS1 and ETS2 proteins in cancer.Cancer reports and reviews · 2018
   Article
9. Molecularly targeted therapies for p53-mutant cancers.Cellular and molecular life sciences : CMLS · 2017
   Review
10. NGS based identification of mutational hotspots for targeted therapy in anaplastic thyroid carcinoma.Oncotarget · 2017
    Article
11. Comparison of human lung cancer cell radiosensitivity after irradiations with therapeutic protons and carbon ions.Experimental biology and medicine (Maywood, N.J.) · 2017
    Article
12. Genome-wide DNA methylation analysis reveals molecular subtypes of pancreatic cancer.Oncotarget · 2017
    Article
13. Identification, validation, and targeting of the mutant p53-PARP-MCM chromatin axis in triple negative breast cancer.NPJ breast cancer · 2017
    Article
14. Mutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
15. Mechanisms of p53 Functional De-Regulation: Role of the IκB-α/p53 Complex.International journal of molecular sciences · 2016
    Review
16. Mutant p53 and ETS2, a Tale of Reciprocity.Frontiers in oncology · 2016
    Review
17. Genetic differences among ethnic groups.BMC genomics · 2015
    Article

Corrections and comments

• Comment on
  Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth.2015

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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