ReviewThe world journal of men's health2015
Glans Penis Augmentation Using Hyaluronic Acid Gel as an Injectable Filler.
Review in The world journal of men's health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Clinical use of hyaluronic acid in andrology: A review.Andrology · 2022Pooled it
- Hyaluronic acid versus botulinum a toxin injection in the treatment of premature ejaculation: A comparative study.Scientific reports · 2025Trial
- Penile prosthesis implantation following conservative surgical treatment for penile cancer: anatomical and surgical considerations.International journal of impotence research · 2025Review
- Foreign Body Granuloma After Polylactic Acid Filler Injection for Penile Girth Enhancement: Three Cases Report.Clinical case reports · 2025Article
- Cosmetic male genital surgery: a narrative review.Annals of translational medicine · 2024Review
- Hyaluronic acid injection to coronal sulcus of the penis for the treatment of premature ejaculation: a retrospective observational study.BMC urology · 2023Observational
- Efficacy of injecting hybrid cooperative complexes of hyaluronic acid for the treatment of vulvar lichen sclerosus: A preliminary study.Journal of cosmetic dermatology · 2023Article
- The Application of Hyaluronic Acid Injections in Functional and Aesthetic Andrology: A Narrative Review.Gels (Basel, Switzerland) · 2023Review
- Current and emerging treatment options for premature ejaculation.Nature reviews. Urology · 2022Review
- Glans penis augmentation: when, how, and why?International journal of impotence research · 2022Review
- Efficacy and Safety of Penile Girth Enhancement Using Hyaluronic Acid Filler and the Clinical Impact on Ejaculation: A Multi-Center, Patient/Evaluator-Blinded, Randomized Active-Controlled Trial.The world journal of men's health · 2022Article
- Human Acellular Dermal Matrix Augmentation Phalloplasty Surgery.Plastic surgery (Oakville, Ont.) · 2020Article
- Progresses in pharmaceutical and surgical management of premature ejaculation.Chinese medical journal · 2019Review
- Complications of glans penis augmentation.International journal of impotence research · 2019Review
- Paraffin Granuloma Associated with Buried Glans Penis-Induced Sexual and Voiding Dysfunction.The world journal of men's health · 2017Article
- Efficacy and safety of a newly developed polylactic acid microsphere as an injectable bulking agent for penile augmentation: 18-months follow-up.International journal of impotence research · 2017Article
- Surgery is not indicated for the treatment of premature ejaculation.Translational andrology and urology · 2016Article
- Complications and management of penile augmentation with hyaluronic acid injection.Asian journal of andrologyArticle
- Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique.Asian journal of andrologyArticle
- Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome.Asian journal of andrologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glans penis augmentation (GPA) has received little attention from experts despite the existence of a subset of patients who may be dissatisfied with a small glans or poor tumescence of the glans during erection. Recently, GPA using an injectable filler or implantation of a graft or filler has been developed. Despite a demanding injection technique and inevitable uneven undulation of the glandular surface, GPA using injectable hyaluronic acid (HA) gel is a novel and useful therapy and an effective and safe procedure for soft tissue enhancement. For long-term presence of implants, timed supplementation can be used similar to that for fascial plasty. In complications such as mucosal necrosis of the glans penis, most cases occur from the use of non-HA gel or an unpurified form and misunderstanding of the management protocol for immediate side effects. Currently, GPA using injectable HA gel is not recommended in the International Society for Sexual Medicine guideline due to possible sensory loss. In a 5-year long-term follow-up of GPA by subcutaneous injection of HA gel, the residual volume of implants decreased by 15% of the maximal glandular circumference, but was still effective for alleviating the hypersensitivity of the glans penis in premature ejaculation patients. For efficacy in premature ejaculation, selection of appropriate candidates is the most important factor for success. GPA does not harm erectile function and is less invasive and irreversible compared to dorsal neurectomy. To refine the procedure, more interest and well-designed studies are required for the establishment of the procedure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.