Evidence map›Paper›PMID 26330848›Full record

ArticleIranian journal of reproductive medicine2015

Association of cord blood levels of IL-17A, but not TGF-β with pre-term neonate.

Masoud Mobini, Sakineh Mirzaie, Hossein Khorramdelazad, Nahid Zainodini, Zahra Sabzali, Mina Ghyasi, Mitra Mokhtari, Reza Bahramabadi, Hamid Hakimi, Khodayar Ghorban and 3 more

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of reproductive medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Masoud MobiniImmunology of Infectious Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Sakineh MirzaieDepartment of Obstetrics and Gynecology, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Hossein KhorramdelazadMolecular Medicine Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Nahid ZainodiniImmunology of Infectious Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Zahra SabzaliDepartment of Obstetrics and Gynecology, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Mina GhyasiDepartment of Obstetrics and Gynecology, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Mitra MokhtariDepartment of Obstetrics and Gynecology, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Reza BahramabadiImmunology of Infectious Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Hamid HakimiImmunology of Infectious Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Khodayar GhorbanDepartment of Immunology, AJA University of Medical Sciences, Tehran, Iran.
Maryam DadmaneshDepartment of Infectious Diseases, AJA University of Medical Sciences, Tehran, Iran.
Vahid EhsaniImmunology of Infectious Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Mohammad Kazemi ArababadiImmunology of Infectious Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Rafsanjan University of Medical Sciences · IRAja University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt has been documented that cytokines play important roles in the induction of normal functions of the placenta. It has been hypothesized that abnormal expression of the cytokines may be associated with unsuccessful pregnancy.

objectiveThe aim of this study was to compare the serum levels of interleukin-17A (IL-17A) and tumor growth factor (TGF-β) in pre-term, term neonates, and their corresponding mothers. MATERIALS AND

methodsThis study was performed on 100 term and 60 pre-term neonates, and also on their corresponded mothers. Serum levels of IL-17A and TGF-β were examined by enzyme linked immunosorbent assay (ELISA).

resultsOur results revealed that the serum levels of IL-17A were significantly decreased in pre-term neonates in comparison to full-term neonates. However, the serum levels of IL-17A in the mothers either with pre-term or full-term neonates were not different. Also the serum levels of TGF-β were not changed in pre-term neonates and their mothers when compared with full-term neonates and their mothers, respectively.

conclusionBased on these findings, it can be concluded that IL-17A may play crucial roles in induction of normal pregnancies and also probably participates in normal growth of fetus.

Indexed as

IL-17APregnancyPre-term deliveryTGF-β

Identifiers

PMID26330848
PMCPMC4555053
OpenAlexW1910853525

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.