Evidence map›Paper›PMID 26330809›Full record

ReviewNeural regeneration research2015

The treatment of Parkinson's disease with deep brain stimulation: current issues.

Alexia-Sabine Moldovan, Stefan Jun Groiss, Saskia Elben, Martin Südmeyer, Alfons Schnitzler, Lars Wojtecki

Abstract readReview
In one paragraph

Review in Neural regeneration research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexia-Sabine MoldovanCenter for Movement Disorders and Neuromodulation, Department of Neurology, University Hospital Düsseldorf, Germany & Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich-Heine University Düsseldorf, Germany.
Stefan Jun GroissCenter for Movement Disorders and Neuromodulation, Department of Neurology, University Hospital Düsseldorf, Germany & Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich-Heine University Düsseldorf, Germany.
Saskia ElbenCenter for Movement Disorders and Neuromodulation, Department of Neurology, University Hospital Düsseldorf, Germany & Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich-Heine University Düsseldorf, Germany.
Martin SüdmeyerCenter for Movement Disorders and Neuromodulation, Department of Neurology, University Hospital Düsseldorf, Germany & Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich-Heine University Düsseldorf, Germany.
Alfons SchnitzlerCenter for Movement Disorders and Neuromodulation, Department of Neurology, University Hospital Düsseldorf, Germany & Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich-Heine University Düsseldorf, Germany.
Lars WojteckiCenter for Movement Disorders and Neuromodulation, Department of Neurology, University Hospital Düsseldorf, Germany & Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich-Heine University Düsseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep brain stimulation has become a well-established symptomatic treatment for Parkinson's disease during the last 25 years. Besides improving motor symptoms and long-term motor complications, positive effects on patients' mobility, activities of daily living, emotional well-being and health-related quality of life have been recognized. Apart from that, numerous clinical trials analyzed effects on non-motor symptoms and side effects of deep brain stimulation. Several technical issues and stimulation paradigms have been and are still being developed to optimize the therapeutic effects, minimize the side effects and facilitate handling. This review summarizes current therapeutic issues, i.e., patient and target selection, surgical procedure and programming paradigms. In addition it focuses on neuropsychological effects and side effects of deep brain stimulation.

Indexed as

deep brain stimulationParkinson's diseasesubthalamic nucleus

Identifiers

PMID26330809
PMCPMC4541217

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.