ReviewJournal of anaesthesiology, clinical pharmacology
Fluid management in patients with trauma: Restrictive versus liberal approach.
Review in Journal of anaesthesiology, clinical pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- Randomised controlled trials in pre-hospital trauma: a systematic mapping review.Scandinavian journal of trauma, resuscitation and emergency medicine · 2021Pooled it
- Pre-hospital transfusion of red blood cells. Part 2: A systematic review of treatment effects on outcomes.Transfusion medicine (Oxford, England) · 2020Pooled it
- Permissive hypotensive resuscitation in adult patients with traumatic haemorrhagic shock: a systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2018Pooled it
- Emergency surgery for blunt abdominal trauma in polytrauma - the impact of time to laparotomy on outcomes.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Biosynthetic blood surrogates: Current status and future opportunities.Bioengineering & translational medicine · 2025Review
- Comparison of whole blood versus red blood cells and plasma to correct trauma-induced coagulopathy ex vivo.Transfusion · 2025Article
- Prehospital Tranexamic Acid Combined with Blood Transfusion Reduced the Short-Term Mortality Risk in Trauma Patients at Risk for Hemorrhage.Therapeutics and clinical risk management · 2025Article
- Review
- Elamipretide mitigates ischemia-reperfusion injury in a swine model of hemorrhagic shock.Scientific reports · 2023Article
- A call for disciplined patience instead of crystalloid infusion for the trauma patient.Journal of military, veteran and family health · 2023Article
- Evaluating Thera-101 as a Low-Volume Resuscitation Fluid in a Model of Polytrauma.International journal of molecular sciences · 2022Article
- Combined Administration of Fibrinogen and Factor XIII Concentrate Does Not Improve Dilutional Coagulopathy Superiorly Than Sole Fibrinogen Therapy: Results of an In-Vitro Thrombelastographic Study.Journal of clinical medicine · 2021Article
- Traumatic Brain Injury-A Review of Intravenous Fluid Therapy.Frontiers in veterinary science · 2021Review
- A Novel Cross-Linked Hemoglobin-Based Oxygen Carrier, YQ23, Extended the Golden Hour for Uncontrolled Hemorrhagic Shock in Rats and Miniature Pigs.Frontiers in pharmacology · 2021Article
- Pre-hospital transfusion of red blood cells. Part 1: A scoping review of current practice and transfusion triggers.Transfusion medicine (Oxford, England) · 2020Article
- The Correlation of Serum Chloride Level and Hospital Mortality in Multiple Trauma Patients.Advanced journal of emergency medicine · 2020Article
- Fluid resuscitation in trauma: what are the best strategies and fluids?International journal of emergency medicine · 2019Review
- Effect of early restrictive fluid resuscitation on inflammatory and immune factors in patients with severe pelvic fracture.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2019Article
- Resuscitation with centhaquin and 6% hydroxyethyl starch 130/0.4 improves survival in a swine model of hemorrhagic shock: a randomized experimental study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2019Article
- [Mechanism of ulinastatin in reducing lung inflammatory injury in rats with hemorrhagic shock].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trauma is a leading cause of death worldwide, and almost 30% of trauma deaths are due to blood loss. A number of concerns have been raised regarding the advisability of the classic principles of aggressive crystalloid resuscitation in traumatic hemorrhagic shock. Some recent studies have shown that early volume restoration in certain types of trauma before definite hemostasis may result in accelerated blood loss, hypothermia, and dilutional coagulopathy. This review discusses the advances and changes in protocols in fluid resuscitation and blood transfusion for treatment of traumatic hemorrhage shock. The concept of low volume fluid resuscitation also known as permissive hypotension avoids the adverse effects of early aggressive resuscitation while maintaining a level of tissue perfusion that although lower than normal, is adequate for short periods. Permissive hypotension is part of the damage control resuscitation strategy, which targets the conditions that exacerbate hemorrhage. The elements of this strategy are permissive hypotension, minimization of crystalloid resuscitation, control of hypothermia, prevention of acidosis, and early use of blood products to minimize coagulopathy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.