Evidence map›Paper›PMID 26329777›Full record

ReviewDaru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences2015

Nanoparticles as potential new generation broad spectrum antimicrobial agents.

Clarence S Yah, Geoffrey S Simate

Abstract readReview
In one paragraph

Review in Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Antiparasitic Activity ofVeterinary sciences · 2026
    Article
  2. Article
  3. Review
  4. Mechanism, Efficacy, and Safety of Natural Antibiotics.Antibiotics (Basel, Switzerland) · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Comparative Study ofNanomaterials (Basel, Switzerland) · 2024
    Article
  9. Novel metal peroxide nanoboxes restrainBioengineering & translational medicine · 2023
    Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. The Use of Metallic Nanoparticles in Wound Healing: New Perspectives.International journal of molecular sciences · 2022
    Article
  15. Review
  16. Review
  17. Review
  18. Frontiers in cellular and infection microbiology · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Clarence S YahDepartment of Biochemistry and Microbiology, Nelson Mandela Metropolitan University, Port Elizabeth, South Africa. cyah@nmmu.ac.za.
Geoffrey S SimateSchool of Chemical and Metallurgical Engineering, University of the Witwatersrand, P/Bag 3, Wits 2050, Johannesburg, South Africa. simateg@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid emergence of antimicrobial resistant strains to conventional antimicrobial agents has complicated and prolonged infection treatment and increased mortality risk globally. Furthermore, some of the conventional antimicrobial agents are unable to cross certain cell membranes thus, restricting treatment of intracellular pathogens. Therefore, the disease-causing-organisms tend to persist in these cells. However, the emergence of nanoparticle (NP) technology has come with the promising broad spectrum NP-antimicrobial agents due to their vast physiochemical and functionalization properties. In fact, NP-antimicrobial agents are able to unlock the restrictions experienced by conventional antimicrobial agents. This review discusses the status quo of NP-antimicrobial agents as potent broad spectrum antimicrobial agents, sterilization and wound healing agents, and sustained inhibitors of intracellular pathogens. Indeed, the perspective of developing potent NP-antimicrobial agents that carry multiple-functionality will revolutionize clinical medicine and play a significant role in alleviating disease burden.

Indexed as

NanoparticlesAnimalsAnti-Infective AgentsHumansWound HealingAnti-Infective Agents

Identifiers

PMID26329777
PMCPMC4557602

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.