ArticleObesity surgery2016
Essential Fatty Acid Plasma Profiles Following Gastric Bypass and Adjusted Gastric Banding Bariatric Surgeries.
Article in Obesity surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Contribution of Malabsorption to Weight Loss After Roux-en-Y Gastric Bypass: a Systematic Review.Obesity surgery · 2017Pooled it
- Differential effects of bariatric surgery and lifestyle interventions on plasma levels of Lp(a) and fatty acids.Lipids in health and disease · 2022Trial
- Alterations in fatty acid metabolism in response to obesity surgery combined with dietary counseling.Nutrition & diabetes · 2017Trial
- Nutritional Status, Selected Nutrients Intake, and Metabolic Disorders in Bariatric Surgery Patients.Nutrients · 2023Article
- Changes in plasma free fatty acids in obese patients before and after bariatric surgery highlight alterations in lipid metabolism.Scientific reports · 2022Article
- The Effects of One-Anastomosis Gastric Bypass on Fatty Acids in the Serum of Patients with Morbid Obesity.Obesity surgery · 2021Article
- Review
- Curbing Obesity from One Generation to Another: the Effects of Bariatric Surgery on the In Utero Environment and Beyond.Reproductive sciences (Thousand Oaks, Calif.) · 2020Review
- Short-Term Effect of One-Anastomosis Gastric Bypass on Essential Fatty Acids in the Serum of Obese Patients.Nutrients · 2020Article
- Roux-en-Y Gastric Bypass Surgery Induces Distinct but Frequently Transient Effects on Acylcarnitine, Bile Acid and Phospholipid Levels.Metabolites · 2018Article
- Proceedings of the 2017 ASPEN Research Workshop-Gastric Bypass: Role of the Gut.JPEN. Journal of parenteral and enteral nutrition · 2018Review
- Potential Application ofScientific reports · 2017Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundAlthough patients experience hair loss and dry skin which may be attributable to deficiency in essential fatty acids (EFAs), the impact of bariatric surgeries on EFA status is unknown.
methodsThis study aimed to assess plasma phospholipid fatty acid profiles following adjustable gastric banding (AGB), which restricts dietary fat intake, versus Roux-en-Y gastric bypass (RYGB), which also promotes fat malabsorption. Serial measures were obtained before and 1 and 6 months from women undergoing RYGB (N = 13) and AGB (N = 5). Measures included the composition of plasma fatty acids in phospholipids, dietary intake, and body fat mass. Friedman and Mann-Whitney tests were used to assess differences over time and between groups, respectively, p < 0.05.
resultsDietary intake of fats decreased equally at 1 and 6 months following RYGB and AGB. By 6 months, the RYGB group lost more body fat. There were no remarkable changes in EFA in plasma phospholipids following AGB. However, following RYGB, a transient increase in 20:4N6 (+18 %) and a decrease in 20:3N6 at 1 (-47 %) and 6 months (-47 %) were observed. Similar changes were observed in N3 fatty acids following RYGB, including a transient increase in 22:6N3 (+11 %) and decreases in 20:5N3 (-79 and -67 % at 1 and 6 months, respectively). EFA status improved following surgery in the RYGB group.
conclusionsWe demonstrate alterations in plasma EFA following RYGB. The status of EFA improved, but the decrease in 20:5N3, the precursor for anti-inflammatory eicosanoids, may be a concern.
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Registered trials
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