Evidence map›Paper›PMID 26328042›Full record

ArticleGastroenterology and hepatology from bed to bench2015

Frequency and risk factors of primary sclerosing cholangitis among patients with inflammatory bowel disease in North-East of Iran.

Ahmad Khosravi Khorashad, Mohammad Khajedaluee, Elham Mokhtari Amirmajdi, Ali Bahari, Mohammad Reza Farzanehfar, Mitra Ahadi, Siavash Abedini, Mohammad Reza Abdollahi, Rosita Vakili, Hassan Vossoughi Nia

Open access · greenAbstract read
In one paragraph

Article in Gastroenterology and hepatology from bed to bench, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ahmad Khosravi KhorashadDepartment of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Ghaem Hospital, Mashhad, Iran.
Mohammad KhajedalueeDepartment of Social Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Elham Mokhtari AmirmajdiGastroenterology and Hepatoloy Department, Nayshabour Faculty of Medical Sciences, Nayshabour, Iran.
Ali BahariEndoscopic & Minimally Invasive Surgery Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Reza FarzanehfarEndoscopic & Minimally Invasive Surgery Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mitra AhadiEndoscopic & Minimally Invasive Surgery Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Siavash AbediniDepartment of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Ghaem Hospital, Mashhad, Iran.
Mohammad Reza AbdollahiDepartment of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Ghaem Hospital, Mashhad, Iran.
Rosita VakiliCenter of Pathological and Medical Diagnostic Services, Iranian Academic Center for Education, Culture & Research (ACECR), Mashhad Branch, Mashhad, Iran.
Hassan Vossoughi NiaEndoscopic & Minimally Invasive Surgery Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ghaem Hospital · IRMashhad University of Medical Sciences · IRAcademic Center for Education, Culture and Research · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo identify primary sclerosing cholangitis (PSC) predisposing factors in order to prevent inflammatory bowel disease (IBD) progression to PSC.

backgroundIBD is commonly associated with PSC and there is no effective therapy for PSC except for liver transplantation. PATIENTS AND

methodsThis retrospective study was conducted on 447 IBD patients from IBD Clinics of Ghaem and Emam Reza Hospitals. Data were collected by interview and through a review of the patients' medical records. Patients were divided into two groups: those with IBD and PSC (IBD-PSC) and those without PSC. Variables were compared between two groups and those with statistically significant differences in IBD-PSC group were considered as predictive factors for the development of PSC.

resultsThe frequency of PSC in IBDs was 4.3% and all were ulcerative colitis. The mean age of patients with PSC was 39.1±11.33 years. The male to female proportion in PSCs was 3.8:1 and in IBDs was 0.9:1. There were statistically significant associations between PSC and gender, IBD duration and UC extension, mucocutaneous involvement, oral contraceptive pills (OCP) consumption, history of surgery and history of PSC in the first- degree relatives.

conclusionPSC frequency among IBD patients in North-East of Iran was 4.3%. It is recommended to limit OCP consumption in IBD patients. Identification and modification of probable predisposing risk factors, as well as early diagnosis of PSC are necessary.

Indexed as

Crohn’s diseaseIBDPrevalencePSCUlcerative colitis

Identifiers

PMID26328042
PMCPMC4553160
OpenAlexW1819934472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.