Evidence map›Paper›PMID 26327875›Full record

ArticlePrzeglad menopauzalny = Menopause review2014

The effect of melatonin supplementation on the quality of sleep and weight status in postmenopausal women.

Ewa Walecka-Kapica, Grażyna Klupińska, Jan Chojnacki, Karolina Tomaszewska-Warda, Aleksandra Błońska, Cezary Chojnacki

Open access · goldAbstract read
In one paragraph

Article in Przeglad menopauzalny = Menopause review, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Melatonin in type 2 diabetes mellitus and obesity.Nature reviews. Endocrinology · 2019
    Review
  11. Article
  12. Melatonin and female hormone secretion in postmenopausal overweight women.International journal of molecular sciences · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ewa Walecka-KapicaDepartment of Clinical Nutrition and Gastroenterological Diagnostic, Medical University of Lodz, Poland.
Grażyna KlupińskaDepartment of Clinical Nutrition and Gastroenterological Diagnostic, Medical University of Lodz, Poland.
Jan ChojnackiDepartment of Clinical Nutrition and Gastroenterological Diagnostic, Medical University of Lodz, Poland.
Karolina Tomaszewska-WardaDepartment of Gastroenterology, Medical University of Lodz, Poland.
Aleksandra BłońskaDepartment of Clinical Nutrition and Gastroenterological Diagnostic, Medical University of Lodz, Poland.
Cezary ChojnackiDepartment of Clinical Nutrition and Gastroenterological Diagnostic, Medical University of Lodz, Poland.
Medical University of Lodz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aim of the studyWe evaluated the effect of melatonin supplementation on the nutritional status of postmenopausal women. MATERIAL AND

methodsThe study included 56 women (51-65 years) and 25 healthy women (27-36 years). The emotional state was assessed using Hamilton Depression Rating Scale (HAM-D), the quality of sleep using Insomnia Severity Index (ISI). Body mass index (BMI) and waist-hip ratio (WHR) were also calculated. The patients were divided into 3 groups: group I (control) - 25 women with normal body weight, group II - 26 postmenopausal women with normal body weight, group III - 30 postmenopausal women with high body weight. In women from group II and III, routine laboratory tests, levels of thyroid-stimulating hormone (TSH), 17β-estradiol, prolactin, follicle-stimulating hormone (FSH) and the concentration of 6-hydroxymelatonin sulphate (6-HMS) in day/night urine fractions were determined. On the day of the examination, women remained on a liquid diet (1800 kcal). Next, a balanced diet of 1500 kcal and 5 mg of melatonin administration were recommended. The follow-up examinations were performed after 4, 8, 12, 16, 20 and 24 weeks.

resultsThe patients from groups II and III showed similar mild levels of anxiety and depression and a significant degree of sleep disorders. In group III, lower urinary 6-HMS excretion was observed at night. In both groups a negative correlation was found between urinary 6-HMS excretion and the degree of sleep disorders. After 24 weeks, a statistically significant improvement of quality of sleep was obtained. A negative correlation was detected between urinary 6-HMS excretion and BMI.

conclusionMelatonin supplementation contributed to body weight reduction.

Indexed as

body mass indexmelatoninmenopausesleep disorders

Identifiers

PMID26327875
PMCPMC4352910
OpenAlexW2125645638

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.