Evidence map›Paper›PMID 26327801›Full record

ArticleActa ortopedica brasileira

Physical and mechanical characterization of a porous cement for metaphyseal bone repair.

Bruno Cimatti, Edgard Eduard Engel, Marcello Henrique Nogueira-Barbosa, Paulo Donato Frighetto, José Batista Volpon

Open access · goldAbstract read
In one paragraph

Article in Acta ortopedica brasileira. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Antibiotic-Releasing Porous Shell Cements.Antibiotics (Basel, Switzerland) · 2026
    Article
  2. [Updates on Bone Grafts and Substitutes].Revista brasileira de ortopedia · 2025
    Article
  3. Updates on Bone Grafts and Substitutes.Revista brasileira de ortopedia · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Bruno CimattiUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Department of Biomechanics, Medicine and Rehabilitation of the Locomotor System, Laboratory of Bioengineering, Ribeirão Preto, SP, Brazil.
Edgard Eduard EngelUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Department of Biomechanics, Medicine and Rehabilitation of the Locomotor System, Laboratory of Bioengineering, Ribeirão Preto, SP, Brazil.
Marcello Henrique Nogueira-BarbosaUniversidade de São Paulo Faculdade de Medicina de Ribeirão Preto, Division of Radiology and Diagnostic Imaging, Ribeirão Preto, SP, Brazil.
Paulo Donato FrighettoInstituto Federal de Educação, Ciência e Tecnologia, Campus Catanduva, SP, Brazil.
José Batista VolponUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Department of Biomechanics, Medicine and Rehabilitation of the Locomotor System, Laboratory of Bioengineering, Ribeirão Preto, SP, Brazil.
Universidade de São Paulo · BRFederal Institute of São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMacroporous cement with mechanical properties similar to cancellous bone may improve the treatment of large bone defects in relation to solid acrylic cement. The aim of this study was to compare physical and mechanical characteristics of a polymethyl methacrylate (PMMA) based porous cement with cancellous bone.

methodsCompressive strength and pore size, interconnectivity, and distribution of cylindrical porous PMMA cement samples containing 10% (G1), 20% (G2) or 30% (G3) effervescent components were analyzed. Results were compared to bovine cancellous bone (G4) and solid PMMA (G5) samples.

resultsScanning electron microscopy (SEM) of all experimental samples (G1 - G3) revealed a random distribution and a wide size variation of pores ranging from 50 µm to 3 mm. Micro-CT showed that G2 have high porosity and lower interconnectivity of pores. No significant differences in yield strength and Young's modulus were observed among G1, G2 and G3. G4 samples were slightly stronger and less elastic than the other groups. Solid PMMA is extremely strong and inelastic.

conclusionsPMMA based porous cement met the expected characteristics. High porosity with large and interconnected pores may allow for bone ingrowth. Strength and elasticity similar to cancellous bone may enhance mechanical stimuli to bone remodeling. Observational Descriptive Study.

Indexed as

Bone neoplasmsBone substitutesBone transplantationPolymethyl methacrylate

Identifiers

PMID26327801
PMCPMC4544528
OpenAlexW1626307020

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.