Evidence map›Paper›PMID 26327774›Full record

SynthesisWorld journal of gastroenterology2015

Systematic review of anastomotic complications of esophagojejunostomy after laparoscopic total gastrectomy.

Mikito Inokuchi, Sho Otsuki, Yoshitaka Fujimori, Yuya Sato, Masatoshi Nakagawa, Kazuyuki Kojima

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 2 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 2 syntheses or guidelines pooled it, 132 citations in OpenAlex.

  1. Pooled it
  2. [Evidence in minimally invasive oncological gastric surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
    Pooled it
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  9. Endoscopic submucosal dissection of a giant gastric polyp.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2025
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  18. [Endoscopic Treatments in Perforation or Fistula in Upper Gastrointestinal Tract].The Korean journal of helicobacter and upper gastrointestinal research · 2024
    Review
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  20. Review

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mikito InokuchiMikito Inokuchi, Sho Otuski, Yoshitaka Fujimori, Yuya Sato, Masatoshi Nakagawa, Department of Surgical Oncology, Tokyo Medical and Dental University, Tokyo 113-8519, Japan.
Sho OtsukiMikito Inokuchi, Sho Otuski, Yoshitaka Fujimori, Yuya Sato, Masatoshi Nakagawa, Department of Surgical Oncology, Tokyo Medical and Dental University, Tokyo 113-8519, Japan.
Yoshitaka FujimoriMikito Inokuchi, Sho Otuski, Yoshitaka Fujimori, Yuya Sato, Masatoshi Nakagawa, Department of Surgical Oncology, Tokyo Medical and Dental University, Tokyo 113-8519, Japan.
Yuya SatoMikito Inokuchi, Sho Otuski, Yoshitaka Fujimori, Yuya Sato, Masatoshi Nakagawa, Department of Surgical Oncology, Tokyo Medical and Dental University, Tokyo 113-8519, Japan.
Masatoshi NakagawaMikito Inokuchi, Sho Otuski, Yoshitaka Fujimori, Yuya Sato, Masatoshi Nakagawa, Department of Surgical Oncology, Tokyo Medical and Dental University, Tokyo 113-8519, Japan.
Kazuyuki KojimaMikito Inokuchi, Sho Otuski, Yoshitaka Fujimori, Yuya Sato, Masatoshi Nakagawa, Department of Surgical Oncology, Tokyo Medical and Dental University, Tokyo 113-8519, Japan.
Tokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the anastomotic complications of esophagojejunostomy (EJS) after laparoscopic total gastrectomy (LTG), we reviewed retrospective studies.

methodsA literature search was conducted in PubMed for studies published from January 1, 1994 through January 31, 2015. The search terms included "laparoscopic," "total gastrectomy," and "gastric cancer." First, we selected 16 non-randomized controlled trials (RCTs) comparing LTG with open total gastrectomy (OTG) and conducted an updated meta-analysis of anastomotic complications after total gastrectomy. The Newcastle-Ottawa scoring system (NOS) was used to assess the quality of the non-RCTs included in this study. Next, we reviewed anastomotic complications in 46 case studies of LTG to compare the various procedures for EJS.

resultsThe overall incidence of anastomotic leakage associated with EJS was 3.0% (30 of 984 patients) among LTG procedures and 2.1% (31 of 1500 patients) among OTG procedures in the 16 non-RCTs. The incidence of anastomotic leakage did not differ significantly between LTG and OTG (odds OR = 1.42, 95%CI: 0.86-2.33, P = 0.17, I(2) = 0%). Anastomotic stenosis related to EJS was reported in 72 (2.9%) of 2484 patients, and the incidence was 3.2% among LTG procedures and 2.7% among OTG procedures. The incidence of anastomotic stenosis related to EJS was slightly, but not significantly, higher in LTG than in OTG (OR = 1.55, 95%CI: 0.94-2.54, P = 0.08, I(2) = 0%). The various procedures for LTG were classified into six categories in the review of case studies of LTG. The incidence of EJS leakage was similar (1.1% to 3.2%), although the incidence of EJS stenosis was relatively high when the OrVil™ device was used (8.8%) compared with other procedures (1.0% to 3.6%).

conclusionThe incidence of anastomotic complications associated with EJS was not different between LTG and OTG. Anastomotic stenosis was relatively common when the OrVil™ device was used.

Indexed as

LaparoscopyAnastomotic LeakChi-Square DistributionConstriction, PathologicEsophagostomyGastrectomyHumansIncidenceJejunostomyOdds RatioRisk FactorsStomach NeoplasmsTreatment OutcomeAnastomosisComplicationGastrectomyGastric cancerLaparoscopic

Identifiers

PMID26327774
PMCPMC4548127
OpenAlexW2418941039

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.