ArticleChemical communications (Cambridge, England)2015
Click with a boronic acid handle: a neighboring group-assisted click reaction that allows ready secondary functionalization.
Article in Chemical communications (Cambridge, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Chemistry of 2-(2'-Aminophenyl)benzothiazole Derivatives: Syntheses, Photophysical Properties and Applications.Molecules (Basel, Switzerland) · 2025Review
- Click chemistry and drug delivery: A bird's-eye view.Acta pharmaceutica Sinica. B · 2023Review
- High-fidelity carbon dots polarity probes: revealing the heterogeneity of lipids in oncology.Light, science & applications · 2022Article
- Design and Development of an HBT-Based Ratiometric Fluorescent Probe to Monitor Stress-Induced Premature Senescence.ACS omega · 2020Article
- Biocompatible conjugation of Tris base to 2-acetyl and 2-formyl phenylboronic acid.Organic & biomolecular chemistry · 2019Article
- Observation of the generation of peroxynitrite in mouse liver after acetaminophen overdose with a boronate-based ratiometric fluorescence probe.RSC advances · 2019Article
- Versatile Bioconjugation Chemistries of ortho-Boronyl Aryl Ketones and Aldehydes.Accounts of chemical research · 2018Article
- Borylated oximes: versatile building blocks for organic synthesis.Chemical communications (Cambridge, England) · 2017Article
- Iminoboronates are efficient intermediates for selective, rapid and reversibleChemical science · 2016Article
- Fast and selective labeling of N-terminal cysteines at neutral pH via thiazolidino boronate formation.Chemical science · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
The feasibility of a neighboring boronic acid-facilitated facile condensation of an aldehyde is described. This reaction is bio-orthogonal, complete at room temperature within minutes, and suitable for bioconjugation chemistry. The boronic acid group serves the dual purpose of catalyzing the condensation reaction and being a handle for secondary functionalization.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.