Evidence map›Paper›PMID 26327446›Full record

ArticleAppetite2016

Food craving and obesity in survivors of pediatric ALL and lymphoma.

Marissa Shams-White, Michael J Kelly, Cheryl Gilhooly, Shanshan Liu, Aviva Must, Susan K Parsons, Edward Saltzman, Fang Fang Zhang

Open access · greenAbstract read
In one paragraph

Article in Appetite, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Altered Food Behavior and Cancer: A Systematic Review of the Literature.International journal of environmental research and public health · 2022
    Pooled it
  2. Article
  3. Article
  4. Review
  5. The evolution of nutritional care in children and young people with acute lymphoblastic leukaemia: a narrative review.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
    Review
  6. Article
  7. Metabolic Implications of Childhood Cancer.Current pediatrics reports · 2025
    Article
  8. Observational
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Marissa Shams-WhiteDepartment of Nutrition Sciences, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Michael J KellyDepartment of Pediatrics, Tufts University School of Medicine, Boston, MA, USA; Division of Pediatric Hematology/Oncology, The Floating Hospital for Children, Tufts Medical Center, Boston, MA, USA.
Cheryl GilhoolyJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA.
Shanshan LiuDepartment of Nutrition Sciences, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.
Aviva MustDepartment of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA.
Susan K ParsonsDepartment of Pediatrics, Tufts University School of Medicine, Boston, MA, USA; Department of Medicine, Tufts University School of Medicine, Boston, MA, USA; Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, USA.
Edward SaltzmanDepartment of Nutrition Sciences, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA; Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA.
Fang Fang ZhangDepartment of Nutrition Sciences, Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA; Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA. Electronic address: fang_fang.zhang@tufts.edu.
Tufts University · USTufts Medical Center · US

Funding

Transgenic CoreP30DK046200 · NIDDK · TUFTS MEDICAL CENTER · PI GREENBERG, ANDREW S, PERISSI, VALENTINA · 1992 to 2021
$25.0M
TUFTS CLINICAL AND TRANSLATION SCIENCE INSTITUTE (UL1): BPCAUL1RR025752 · NCRR · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2008 to 2011
$17.6M
Effect of Aging on Preadipocyte DifferentiationR37AG013925 · NIA · MAYO CLINIC ROCHESTER · PI KIRKLAND, JAMES L. · 2016 to 2025
$6.6M
Tufts Clinical and Translation Science Institute (UL1)UL1TR000073 · NCATS · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2012 to 2013
$5.5M
NCATS NIH HHS UL1 TR000073NCRR NIH HHS UL1 RR025752NIA NIH HHS R37 AG013925NIDDK NIH HHS P30 DK046200NIDDK NIH HHS P30DK46200
6 · The paper itself

Abstract

Cancer treatment can impact the hypothalamic-pituitary region of the developing brain, impairing appetite regulation and causing food craving in children who have survived cancer. We assessed food craving using a modified Food Craving Inventory in 22 survivors of pediatric acute lymphoblastic leukemia (ALL) and lymphoma (median age = 11.7 years) and evaluated its association with treatment exposure and changes in weight status over a one-year period. Mean total craving score was 2.1 (SD = 0.7). Survivors reported significantly higher mean craving score for fast-foods [2.6 (SD = 0.9)] than for sweets [2.1 (SD = 0.8)], carbohydrates [2.0 (SD = 0.6)], and fats [1.8 (SD = 0.7)] (all P values < 0.05). Results from multivariate linear regression indicated that survivors diagnosed at an older age (≥4.5 years) experienced higher frequencies of food craving than those diagnosed at a younger age (<4.5 years) (β = 0.88, 95% CI: 0.42, 1.34). Food craving, however, was not significantly associated with survivors' weight status over 12 months of follow-up. Food craving alone does not appear to explain the obesity risk in this sample of childhood cancer survivors. The role of food craving in shaping eating behavior and obesity risk needs to be further evaluated in a large cohort of childhood cancer survivors.

Indexed as

CravingAdolescentAntineoplastic AgentsBody Mass IndexBody WeightChildDiet SurveysFeeding BehaviorFemaleFollow-Up StudiesFood PreferencesHumansLong Term Adverse EffectsLymphomaMaleObesityAntineoplastic AgentsChildhood cancerFood cravingNutritionObesity

Identifiers

PMID26327446
PMCPMC4684764
OpenAlexW1481603067

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.