Evidence map›Paper›PMID 26327127›Full record

Trial reportPloS one2015

Acceptance of Combined Coronary CT Angiography and Myocardial CT Perfusion versus Conventional Coronary Angiography in Patients with Coronary Stents--Intraindividual Comparison.

Matthias Rief, Sarah Feger, Peter Martus, Michael Laule, Marc Dewey, Eva Schönenberger

Registry-linked trialOpen access · goldAbstract readClinical TrialComparative Study
In one paragraph

Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00967876 (Coronary Artery Stent Evaluation With 320-slice Computed Tomography - The CArS 320 Study), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00967876 completednot on this map

Coronary Artery Stent Evaluation With 320-slice Computed Tomography - The CArS 320 Study

TypeobservationalSponsorCharite University, Berlin, GermanyRan2009Enrolled90ConditionsCoronary Artery Stenosis
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Matthias RiefDepartment of Radiology, Charité, Medical School, Berlin, Germany.
Sarah FegerDepartment of Radiology, Charité, Medical School, Berlin, Germany.
Peter MartusInstitute for Clinical Epidemiology and Applied Biostatistics, Eberhard Karls University Tübingen, Germany.
Michael LauleDepartment of Cardiology, Charité, Medical School, Berlin, Germany.
Marc DeweyDepartment of Radiology, Charité, Medical School, Berlin, Germany.
Eva SchönenbergerDepartment of Medicine, Medical School Hannover, Hannover, Germany.
MSB Medical School Berlin · DEMedizinische Hochschule Hannover · DEUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate how well patients with coronary stents accept combined coronary computed tomography angiography (CTA) and myocardial CT perfusion (CTP) compared with conventional coronary angiography (CCA).

backgroundWhile combined CTA and CTP may improve diagnostic accuracy compared with CTA alone, patient acceptance of CTA/CTP remains to be defined.

methodsA total of 90 patients with coronary stents prospectively underwent CTA/CTP (both with contrast agent, CTP with adenosine) and CCA as part of the CARS-320 study. In this group, an intraindividual comparison of patient acceptance of CTA, CTP, and CCA was performed.

resultsCTP was experienced to be significantly more painful than CTA (p<0.001) and was associated with a higher frequency of dyspnea (p<0.001). Comparison of CTA/CTP with CCA revealed no significant differences in terms of pain (p = 0.141) and comfort (p = 0.377). Concern before CTA/CTP and CCA and overall satisfaction were likewise not significantly different (p = 0.097 and p = 0.123, respectively). Nevertheless, about two thirds (n = 60, 68%) preferred CTA/CTP to CCA (p<0.001). Moreover, patients felt less helpless during CTA/CTP than during CCA (p = 0.026). Lack of invasiveness and absence of pain were the most frequently mentioned advantages of CTA/CTP over CCA in our patient population.

conclusionsCCA and combined CTA/CTP are equally well accepted by patients; however, more patients prefer CTA/CTP. CTP was associated with more intense pain than CTA and more frequently caused dyspnea than CTA alone.

trial registrationClinicalTrials.gov NCT00967876.

Indexed as

Blood Vessel ProsthesisStentsAgedCoronary AngiographyCoronary DiseaseFemaleHumansMaleMiddle AgedMyocardial Perfusion ImagingPainPatient Acceptance of Health CarePatient PreferencePatient SatisfactionSurveys and QuestionnairesTomography, X-Ray Computed

Identifiers

PMID26327127
PMCPMC4556695
OpenAlexW2164746859

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.