Evidence map›Paper›PMID 26325175›Full record

ArticleHuman vaccines & immunotherapeutics2016

Serotype distribution of Streptococcus pneumoniae in children with invasive diseases in Turkey: 2008-2014.

Mehmet Ceyhan, Yasemin Ozsurekci, Nezahat Gürler, Lütfiye Öksüz, Sohret Aydemir, Sengul Ozkan, Serife Yuksekkaya, Melike Keser Emiroglu, Meral Gültekin, Akgün Yaman and 20 more

Abstract readMulticenter Study
In one paragraph

Article in Human vaccines & immunotherapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Serotype distribution ofHuman vaccines & immunotherapeutics · 2026
    Article
  3. Article
  4. Review
  5. Serotype distribution ofAnnals of medicine · 2023
    Article
  6. Epidemiology ofVaccines · 2023
    Article
  7. Article
  8. Observational
  9. Serotype distribution ofHuman vaccines & immunotherapeutics · 2020
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Molecular characteristics of penicillin-binding protein 2b, 2x and 1a sequences in Streptococcus pneumoniae isolates causing invasive diseases among children in Northeast China.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Mehmet Ceyhana Department of Pediatric Infectious Diseases ; Hacettepe University Faculty of Medicine ; Ankara , Turkey.
Yasemin Ozsurekcia Department of Pediatric Infectious Diseases ; Hacettepe University Faculty of Medicine ; Ankara , Turkey.
Nezahat Gürlerb Department of Microbiology and Clinical Microbiology ; Istanbul University Faculty of Medicine ; Istanbul , Turkey.
Lütfiye Öksüzb Department of Microbiology and Clinical Microbiology ; Istanbul University Faculty of Medicine ; Istanbul , Turkey.
Sohret Aydemirc Department of Microbiology and Clinical Microbiology ; Ege University Faculty of Medicine ; Izmir , Turkey.
Sengul Ozkand Microbiology Laboratory; Dr. Sami Ulus Children's Health and Diseases Training and Research Hospital ; Ankara , Turkey.
Serife Yuksekkayae Microbiology; Konya Training and Research Hospital ; Konya , Turkey.
Melike Keser Emirogluf Department of Pediatric Infectious Diseases ; Selçuk University Faculty of Medicine ; Konya , Turkey.
Meral Gülteking Department of Medical Microbiology ; Akdeniz University Faculty of Medicine ; Antalya , Turkey.
Akgün Yamanh Department of Microbiology ; Çukurova University Faculty of Medicine ; Adana , Turkey.
Abdurrahman Kiremitcii Department of Microbiology , Osmangazi University Faculty of Medicine , Izmir , Turkey.
Keramettin Yanıkj Department of Microbiology ; Ondokuz Mayıs University Faculty of Medicine ; Samsun , Turkey.
Arzu Karlij Department of Microbiology ; Ondokuz Mayıs University Faculty of Medicine ; Samsun , Turkey.
Hatice Ozcinark Microbiology Laboratory; Sanliurfa Children's Hospital ; Sanliurfa , Turkey.
Faruk Aydinl Department of Medical Microbiology ; Karadeniz Technical University Faculty of Medicine ; Trabzon , Turkey.
Gulcin Bayramoglul Department of Medical Microbiology ; Karadeniz Technical University Faculty of Medicine ; Trabzon , Turkey.
Yasemin Zerm Department of Microbiology ; Gaziantep University Faculty of Medicine ; Gaziantep , Turkey.
Zeynep Gulayn Department of Microbiology ; Dokuzeylül University Faculty of Medicine ; Izmir , Turkey.
Efgan Dogan Gayyurhano Microbiology Laboratory; Gaziantep Children's Hospital ; Gaziantep , Turkey.
Mustafa Gülp Department of Microbiology ; Sutcuimam University Faculty of Medicine ; Kahramanmaras , Turkey.
Cüneyt Özakınq Department of Medical Microbiology ; Uludağ University Faculty of Medicine ; Bursa , Turkey.
Hüseyin Güdücüoğlur Department of Microbiology ; Yüzüncü Yıl University Faculty of Medicine Training Hospital ; Van , Turkey.
Duygu Perçins Central Laboratory, Bacteriology; Erciyes University Faculty of Medicine ; Kayseri , Turkey.
Nezahat Akpolatt Department of Microbiology ; Dicle University Faculty of Medicine ; Diyarbakir , Turkey.
Candan Ozturku Department of Medical Microbiology ; Mersin University Faculty of Medicine ; Mersin , Turkey.
Yıldız Camcıoğluv Department of Pediatrics ; Istanbul University Cerrahpasa Faculty of Medicine ; Istanbul , Turkey.
Eda Karadağ Öncela Department of Pediatric Infectious Diseases ; Hacettepe University Faculty of Medicine ; Ankara , Turkey.
Melda Çelika Department of Pediatric Infectious Diseases ; Hacettepe University Faculty of Medicine ; Ankara , Turkey.
Laser Şanalw Microbiology Laboratory; Dr. Dogan Baran Hospital for Women's and Children's Diseases ; Niğde , Turkey.
Hakan Uslux Department of Microbiology ; Ataturk University Faculty of Medicine ; Erzurum , Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Successful vaccination policies for protection from invasive pneumococcal diseases (IPD) dependent on determination of the exact serotype distribution in each country. We aimed to identify serotypes of pneumococcal strains causing IPD in children in Turkey and emphasize the change in the serotypes before and after vaccination with 7-valent pneumococcal conjugate vaccine (PCV-7) was included and PCV-13 was newly changed in Turkish National Immunization Program. Streptococcus pneumoniae strains were isolated at 22 different hospitals of Turkey, which provide healthcare services to approximately 65% of the Turkish population. Of the 335 diagnosed cases with S. pneumoniae over the whole period of 2008-2014, the most common vaccine serotypes were 19F (15.8%), 6B (5.9%), 14 (5.9%), and 3 (5.9%). During the first 5 y of age, which is the target population for vaccination, the potential serotype coverage ranged from 57.5 % to 36.8%, from 65.0% to 44.7%, and from 77.4% to 60.5% for PCV-7, PCV-10, and PCV-13 in 2008-2014, respectively. The ratio of non-vaccine serotypes was 27.2% in 2008-2010 whereas was 37.6% in 2011-2014 (p=0.045). S. penumoniae serotypes was less non-susceptible to penicillin as compared to our previous results (33.7 vs 16.5 %, p=0.001). The reduction of those serotype coverage in years may be attributed to increasing vaccinated children in Turkey and the increasing non-vaccine serotype may be explained by serotype replacement. Our ongoing IPD surveillance is a significant source of information for the decision-making processes on pneumococcal vaccination.

Indexed as

Anti-Bacterial AgentsChild, PreschoolFemaleHeptavalent Pneumococcal Conjugate VaccineHospitalsHumansImmunization ProgramsMaleMicrobial Sensitivity TestsPneumococcal InfectionsPneumococcal VaccinesProspective StudiesSerogroupStreptococcus pneumoniaeTurkeyVaccination10-valent pneumococcal conjugate vaccine13-valent pneumococcal vaccineAnti-Bacterial AgentsHeptavalent Pneumococcal Conjugate VaccinePneumococcal VaccinesVaccines, ConjugateepidemiologyserotypesS. pneumoniaesurveillanceTurkey

Identifiers

PMID26325175
PMCPMC5049732

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.