Evidence map›Paper›PMID 26325155›Full record

ArticleAmerican journal of respiratory and critical care medicine2015

A Genome-Wide Association Study of Post-bronchodilator Lung Function in Children with Asthma.

John M Brehm, Sze Man Tse, Damien C Croteau-Chonka, Erick Forno, Augusto A Litonjua, Benjamin A Raby, Wei Chen, Qi Yan, Nadia Boutaoui, Edna Acosta-Pérez and 12 more

Abstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

John M Brehm1 University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania.
Sze Man Tse2 Harvard Medical School Boston, Massachusetts.
Damien C Croteau-Chonka2 Harvard Medical School Boston, Massachusetts.
Erick Forno1 University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania.
Augusto A Litonjua2 Harvard Medical School Boston, Massachusetts.
Benjamin A Raby2 Harvard Medical School Boston, Massachusetts.
Wei Chen1 University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania.
Qi Yan1 University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania.
Nadia Boutaoui1 University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania.
Edna Acosta-Pérez3 University of Puerto Rico San Juan, Puerto Rico.
Lydiana Avila4 Hospital Nacional de Niños San José, Costa Rica.
Scott T Weiss2 Harvard Medical School Boston, Massachusetts.
Manuel Soto-Quiros4 Hospital Nacional de Niños San José, Costa Rica.
Michelle M Cloutier5 University of Connecticut Health Center Farmington, Connecticut.
Donglei Hu6 University of California at San Francisco San Francisco, California.
Maria Pino-Yanes6 University of California at San Francisco San Francisco, California.
Sally E Wenzel1 University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania.
Melissa L Spear6 University of California at San Francisco San Francisco, California.
Jay K Kolls1 University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania.
Esteban G Burchard6 University of California at San Francisco San Francisco, California.
Glorisa Canino3 University of Puerto Rico San Juan, Puerto Rico.
Juan C Celedón1 University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania.

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
THE PHARMACOGENETICS OF ASTHMA TREATMENTU01HL065899 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI TANTISIRA, KELAN G, WEISS, SCOTT T · 2000 to 2014
$38.5M
The Genetic Epidemiology of Asthma in Costa RicaR37HL066289 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISS, SCOTT T · 2007 to 2015
$14.6M
Statistical GeneticsP01HL083069 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISS, SCOTT T · 2007 to 2011
$12.2M
The Airway Functional Genomics of Bronchodilator Drug Response in Minority Children with AsthmaR01HL117004 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AHITUV, NADAV, SEIBOLD, MAX A · 2013 to 2022
$9.3M
CLINICAL, PHARMACOLOGY, DRUG ACTION &PHARMACOKINETICST32GM007546 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Radojka Savic · 1985 to 2026
$8.9M
Genetics and Gene Expression Profiling in AsthmaR01HL086601 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI RABY, BENJAMIN ALEXANDER · 2007 to 2015
$6.8M
Social Interventions to address disparities In young adult tobacco useP60MD006902 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BIBBINS-DOMINGO, KIRSTEN · 2012 to 2016
$6.4M
Epigenetic Variation and Childhood Asthma in Puerto RicansR01HL117191 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS · 2013 to 2020
$5.8M
Gene-environments and Admixture in Latino Asthmatics (GALA 2)R01ES015794 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2008 to 2012
$5.4M
THE GENETIC EPIDEMIOLOGY OF ASTHMA IN COSTA RICAR01HL066289 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISS, SCOTT T · 2001 to 2005
$5.2M
Whole Genome Analyses for Asthma in Latino PopulationsR01HL088133 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2008 to 2012
$3.8M
NCATS NIH HHS UL1 TR000005NHLBI NIH HHS HL004464NHLBI NIH HHS HL04370NHLBI NIH HHS HL066289NHLBI NIH HHS HL079966NHLBI NIH HHS HL088133NHLBI NIH HHS HL117004NHLBI NIH HHS HL117191NHLBI NIH HHS K01 HL004370NHLBI NIH HHS K08 HL111201NHLBI NIH HHS K08HL111201NHLBI NIH HHS K23 HL004464NHLBI NIH HHS P01 HL083069NHLBI NIH HHS R01 HL066289NHLBI NIH HHS R01 HL079966NHLBI NIH HHS R01 HL086601NHLBI NIH HHS R01 HL088133NHLBI NIH HHS R01 HL117004NHLBI NIH HHS R01 HL117191NHLBI NIH HHS R37 HL066289NHLBI NIH HHS U01 HL065899NHLBI NIH HHS U01 HL075419NHLBI NIH HHS U01 HL65899NIEHS NIH HHS ES015794NIEHS NIH HHS R01 ES015794NIGMS NIH HHS GM007546NIGMS NIH HHS T32 GM007546NIMHD NIH HHS MD006902NIMHD NIH HHS P60 MD006902
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAdultAlbuterolAsthmaBronchodilator AgentsCarrier ProteinsChildCystic Fibrosis Transmembrane Conductance RegulatorFemaleFibroblast Growth FactorsForced Expiratory VolumeGenome-Wide Association StudyHispanic or LatinoHumansHypoxanthine PhosphoribosyltransferaseIntracellular Signaling Peptides and ProteinsAlbuterolBronchodilator AgentsCarrier ProteinsCFTR protein, humanCystic Fibrosis Transmembrane Conductance Regulatorfibroblast growth factor 14Fibroblast Growth FactorsGSTCD protein, humanHypoxanthine PhosphoribosyltransferaseIntracellular Signaling Peptides and ProteinsINTS12 protein, humanProteins

Identifiers

PMID26325155
PMCPMC4595689

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.