ArticleProceedings of the National Academy of Sciences of the United States of America2015
The genome of Aiptasia, a sea anemone model for coral symbiosis.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 217 papers.
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Who cites it
217 citing papers in PubMed, 465 citations in OpenAlex.
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- Cosmopolitan Gene Families With Known Functions Are Hotspots for the Evolution of Novel Genes in Stony Corals.Genome biology and evolution · 2026Article
- Thermal Stress-Induced Alterations to Oxylipin Signal Receptors in the Cnidarian-Dinoflagellate Symbiosis.Environmental microbiology · 2026Article
- The first chromosome-level cubozoan genome differentiates unique and common features in different cnidarian lineages.BMC biology · 2026Article
- Symbiotic state affects microbiome recovery in a facultatively symbiotic cnidarian.Scientific reports · 2026Article
- Manganese supplementation enhances cnidarian-dinoflagellate symbiosis under thermal stress.Communications biology · 2026Article
- Trait-based signatures associated with persistence and thermal benefit in a genomically decayed coral probiotic.The ISME journal · 2026Article
- Symbiont Identity Impacts Prokaryotic Microbiome Dynamics During Heat Stress in a Model System for Corals.Integrative and comparative biology · 2026Article
- Heterotrophy and symbiosis affect energy reserves for pedal lacerates in the sea anemonePeerJ · 2026Article
- The genome of the reef-building coralGigaByte (Hong Kong, China) · 2026Article
- Integrins mediate symbiont-specific uptake in cnidarian larvae.EMBO reports · 2026Article
- The genome of the coral model sea anemoneGigaByte (Hong Kong, China) · 2026Article
- The nascent RNA labelling compound 5-ethynyl uridine (EU) integrates into DNA in some animals.BMC molecular and cell biology · 2025Article
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- Cnidaria-Inspired Morphing Mechanism for Underwater Robot: A Soft Tectonics Approach.Sensors (Basel, Switzerland) · 2025Article
- Sterols are key to coral larvae survival, swimming capacity, and thermal tolerance.Communications biology · 2025Article
- Heat Stress Drives Rapid Viral and Antiviral Innate Immunity Activation in Hexacorallia.Molecular ecology · 2025Article
157 more citing papers are in PubMed but not listed here.
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Authors and funding
15 authors at 5 institutions in 4 countries.
Funding
Abstract
The most diverse marine ecosystems, coral reefs, depend upon a functional symbiosis between a cnidarian animal host (the coral) and intracellular photosynthetic dinoflagellate algae. The molecular and cellular mechanisms underlying this endosymbiosis are not well understood, in part because of the difficulties of experimental work with corals. The small sea anemone Aiptasia provides a tractable laboratory model for investigating these mechanisms. Here we report on the assembly and analysis of the Aiptasia genome, which will provide a foundation for future studies and has revealed several features that may be key to understanding the evolution and function of the endosymbiosis. These features include genomic rearrangements and taxonomically restricted genes that may be functionally related to the symbiosis, aspects of host dependence on alga-derived nutrients, a novel and expanded cnidarian-specific family of putative pattern-recognition receptors that might be involved in the animal-algal interactions, and extensive lineage-specific horizontal gene transfer. Extensive integration of genes of prokaryotic origin, including genes for antimicrobial peptides, presumably reflects an intimate association of the animal-algal pair also with its prokaryotic microbiome.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.