Evidence map›Paper›PMID 26324724›Full record

ArticleThe American journal of tropical medicine and hygiene2015

Genomic Characterization of Yogue, Kasokero, Issyk-Kul, Keterah, Gossas, and Thiafora Viruses: Nairoviruses Naturally Infecting Bats, Shrews, and Ticks.

Peter J Walker, Steven G Widen, Cadhla Firth, Kim R Blasdell, Thomas G Wood, Amelia P A Travassos da Rosa, Hilda Guzman, Robert B Tesh, Nikos Vasilakis

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 45 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Peter J WalkerCSIRO Biosecurity, Australian Animal Health Laboratory, Geelong, Victoria, Australia; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas; Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, The University of Texas Medical Branch, Galveston, Texas; Center for Tropical Diseases, Institute for Human Infections and Immunity, The University of Texas Medical Branch, Galveston, Texas peter.walker@csiro.au.
Steven G WidenCSIRO Biosecurity, Australian Animal Health Laboratory, Geelong, Victoria, Australia; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas; Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, The University of Texas Medical Branch, Galveston, Texas; Center for Tropical Diseases, Institute for Human Infections and Immunity, The University of Texas Medical Branch, Galveston, Texas.
Cadhla FirthCSIRO Biosecurity, Australian Animal Health Laboratory, Geelong, Victoria, Australia; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas; Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, The University of Texas Medical Branch, Galveston, Texas; Center for Tropical Diseases, Institute for Human Infections and Immunity, The University of Texas Medical Branch, Galveston, Texas.
Kim R BlasdellCSIRO Biosecurity, Australian Animal Health Laboratory, Geelong, Victoria, Australia; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas; Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, The University of Texas Medical Branch, Galveston, Texas; Center for Tropical Diseases, Institute for Human Infections and Immunity, The University of Texas Medical Branch, Galveston, Texas.
Thomas G WoodCSIRO Biosecurity, Australian Animal Health Laboratory, Geelong, Victoria, Australia; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas; Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, The University of Texas Medical Branch, Galveston, Texas; Center for Tropical Diseases, Institute for Human Infections and Immunity, The University of Texas Medical Branch, Galveston, Texas.
Amelia P A Travassos da RosaCSIRO Biosecurity, Australian Animal Health Laboratory, Geelong, Victoria, Australia; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas; Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, The University of Texas Medical Branch, Galveston, Texas; Center for Tropical Diseases, Institute for Human Infections and Immunity, The University of Texas Medical Branch, Galveston, Texas.
Hilda GuzmanCSIRO Biosecurity, Australian Animal Health Laboratory, Geelong, Victoria, Australia; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas; Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, The University of Texas Medical Branch, Galveston, Texas; Center for Tropical Diseases, Institute for Human Infections and Immunity, The University of Texas Medical Branch, Galveston, Texas.
Robert B TeshCSIRO Biosecurity, Australian Animal Health Laboratory, Geelong, Victoria, Australia; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas; Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, The University of Texas Medical Branch, Galveston, Texas; Center for Tropical Diseases, Institute for Human Infections and Immunity, The University of Texas Medical Branch, Galveston, Texas.
Nikos VasilakisCSIRO Biosecurity, Australian Animal Health Laboratory, Geelong, Victoria, Australia; Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas; Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, The University of Texas Medical Branch, Galveston, Texas; Center for Tropical Diseases, Institute for Human Infections and Immunity, The University of Texas Medical Branch, Galveston, Texas.
The University of Texas Medical Branch at Galveston · US

Funding

NIAID NIH HHS HHSN272201000040I
6 · The paper itself

Abstract

The genus Nairovirus of arthropod-borne bunyaviruses includes the important emerging human pathogen, Crimean-Congo hemorrhagic fever virus (CCHFV), as well as Nairobi sheep disease virus and many other poorly described viruses isolated from mammals, birds, and ticks. Here, we report genome sequence analysis of six nairoviruses: Thiafora virus (TFAV) that was isolated from a shrew in Senegal; Yogue (YOGV), Kasokero (KKOV), and Gossas (GOSV) viruses isolated from bats in Senegal and Uganda; Issyk-Kul virus (IKV) isolated from bats in Kyrgyzstan; and Keterah virus (KTRV) isolated from ticks infesting a bat in Malaysia. The S, M, and L genome segments of each virus were found to encode proteins corresponding to the nucleoprotein, polyglycoprotein, and polymerase protein of CCHFV. However, as observed in Leopards Hill virus (LPHV) and Erve virus (ERVV), polyglycoproteins encoded in the M segment lack sequences encoding the double-membrane-spanning CCHFV NSm protein. Amino acid sequence identities, complement-fixation tests, and phylogenetic analysis indicated that these viruses cluster into three groups comprising KKOV, YOGV, and LPHV from bats of the suborder Yingochiroptera; KTRV, IKV, and GOSV from bats of the suborder Yangochiroptera; and TFAV and ERVV from shrews (Soricomorpha: Soricidae). This reflects clade-specific host and vector associations that extend across the genus.

Indexed as

Amino Acid SequenceAnimalsBase SequenceBunyaviridae InfectionsChiropteraGenome, ViralGenomicsHumansKyrgyzstanMalaysiaNairovirusNucleoproteinsPhylogenySenegalSequence AlignmentSequence Analysis, DNANucleoproteinsViral Proteins

Identifiers

PMID26324724
PMCPMC4703270
OpenAlexW2180896158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.