Evidence map›Paper›PMID 26324339›Full record

ArticleBMC veterinary research2015

International veterinary epilepsy task force recommendations for systematic sampling and processing of brains from epileptic dogs and cats.

Kaspar Matiasek, Martí Pumarola I Batlle, Marco Rosati, Francisco Fernández-Flores, Andrea Fischer, Eva Wagner, Mette Berendt, Sofie F M Bhatti, Luisa De Risio, Robyn G Farquhar and 12 more

Abstract read
In one paragraph

Article in BMC veterinary research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Dogs as a Natural Animal Model of Epilepsy.Frontiers in veterinary science · 2022
    Review
  11. Article
  12. Article
  13. A hypomyelinating leukodystrophy in German Shepherd dogs.Journal of veterinary internal medicine · 2021
    Article
  14. Companion animal models of neurological disease.Journal of neuroscience methods · 2020
    Review
  15. Article
  16. Article
  17. Article
  18. Generalized myoclonic epilepsy with photosensitivity in juvenile dogs caused by a defective DIRAS family GTPase 1.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Kaspar MatiasekSection of Clinical and Comparative Neuropathology, Centre for Clinical Veterinary Medicine, Ludwig-Maximilians-University, Veterinärstr. 13, 80539, Munich, Germany. kaspar.matiasek@neuropathologie.de.
Martí Pumarola I BatlleDepartment of Animal Medicine and Surgery, Veterinary Faculty, Universitat Autònoma de Barcelona, Campus UAB Bellaterra, 08193, Barcelona, Spain. marti.pumarola@uab.cat.
Marco RosatiSection of Clinical and Comparative Neuropathology, Centre for Clinical Veterinary Medicine, Ludwig-Maximilians-University, Veterinärstr. 13, 80539, Munich, Germany. marco.rosati@neuropathologie.de.
Francisco Fernández-FloresDepartment of Animal Medicine and Surgery, Veterinary Faculty, Universitat Autònoma de Barcelona, Campus UAB Bellaterra, 08193, Barcelona, Spain. Francisco.Fernandez.Flores@uab.cat.
Andrea FischerDepartment of Animal and Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark. andreafischer@lmu.de.
Eva WagnerSection of Clinical and Comparative Neuropathology, Centre for Clinical Veterinary Medicine, Ludwig-Maximilians-University, Veterinärstr. 13, 80539, Munich, Germany. eva.wagner@neuropathologie.de.
Mette BerendtDepartment of Animal and Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark. mbe@sund.ku.dk.
Sofie F M BhattiDepartment of Small Animal Medicine and Clinical Biology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke, 9820, Belgium. sofie.bhatti@ugent.be.
Luisa De RisioAnimal Health Trust, Lanwades Park, Kentford, Newmarket, CB8 7UU, Suffolk, UK. luisa.derisio@aht.org.uk.
Robyn G FarquharFernside Veterinary Centre, 205 Shenley Road, Borehamwood, SG9 0TH, Hertfordshire, UK. robyn.fernside@googlemail.com.
Sam LongUniversity of Melbourne, 250 Princes Highway, Weibee, 3015, VIC, Australia. snlong@unimelb.edu.au.
Karen MuñanaNorth Carolina State University, 1052 William Moore Drive, Raleigh, NC, 27607, USA. krmunana@ncsu.edu.
Edward E PattersonUniversity of Minnesota College of Veterinary Medicine, D426 Veterinary Medical Center, 1352 Boyd Avenue, St. Paul, MN, 55108, USA. patte037@umn.edu.
Akos PakozdyClinical Unit of Internal Medicine Small Animals, University of Veterinary Medicine, Veterinärplatz 1, 1210, Vienna, Austria. akos.pakozdy@vetmeduni.ac.at.
Jacques PenderisVet Extra Neurology, Broadleys Veterinary Hospital, Craig Leith Road, Stirling, FK7 7LE, Stirlingshire, UK. jacques.penderis@vet-neurology.co.uk.
Simon PlattCollege of Veterinary Medicine, University of Georgia, 501 DW Brooks Drive, Athens, GA, 30602, USA. srplatt@uga.edu.
Michael PodellChicago Veterinary Neurology and Neurosurgery, 3123 N. Clybourn Avenue, Chicago, IL, 60618, USA. mpodell@comcast.net.
Heidrun PotschkaDepartment of Pharmacology, Toxicology and Pharmacy, Ludwig-Maximillians-University, Königinstr. 16, 80539, Munich, Germany. potschka@pharmtox.vetmed.uni-muenchen.de.
Clare RusbridgeFitzpatrick Referrals, Halfway Lane, Eashing, Godalming, GU7 2QQ, Surrey, UK. ClareR@fitzpatrickreferrals.co.uk.
Veronika M SteinDepartment of Small Animal Medicine and Surgery, University of Veterinary Medicine Hannover, Bünteweg 9, 30559, Hannover, Germany. Veronika.Stein@tiho-hannover.de.
Andrea TipoldDepartment of Small Animal Medicine and Surgery, University of Veterinary Medicine Hannover, Bünteweg 9, 30559, Hannover, Germany. Andrea.Tipold@tiho-hannover.de.
Holger A VolkDepartment of Clinical Science and Services, Royal Veterinary College, Hatfield, AL9 7TA, Hertfordshire, UK. hvolk@rvc.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditionally, histological investigations of the epileptic brain are required to identify epileptogenic brain lesions, to evaluate the impact of seizure activity, to search for mechanisms of drug-resistance and to look for comorbidities. For many instances, however, neuropathological studies fail to add substantial data on patients with complete clinical work-up. This may be due to sparse training in epilepsy pathology and or due to lack of neuropathological guidelines for companion animals.The protocols introduced herein shall facilitate systematic sampling and processing of epileptic brains and therefore increase the efficacy, reliability and reproducibility of morphological studies in animals suffering from seizures.Brain dissection protocols of two neuropathological centres with research focus in epilepsy have been optimised with regards to their diagnostic yield and accuracy, their practicability and their feasibility concerning clinical research requirements.The recommended guidelines allow for easy, standardised and ubiquitous collection of brain regions, relevant for seizure generation. Tissues harvested the prescribed way will increase the diagnostic efficacy and provide reliable material for scientific investigations.

Indexed as

AnimalsBrainCat DiseasesCatsDog DiseasesDogsEpilepsySpecimen Handling

Identifiers

PMID26324339
PMCPMC4595046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.