Evidence map›Paper›PMID 26324271›Full record

ArticleAntimicrobial agents and chemotherapy2015

Novel plasmid-borne multidrug resistance gene cluster including lsa(E) from a linezolid-resistant Enterococcus faecium isolate of swine origin.

Hongbin Si, Wan-Jiang Zhang, Shengbo Chu, Xiu-Mei Wang, Lei Dai, Xin Hua, Zhimin Dong, Stefan Schwarz, Siguo Liu

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. TnAntimicrobial agents and chemotherapy · 2022
    Article
  11. Characterization and Comparison ofAnimals : an open access journal from MDPI · 2021
    Article
  12. A Conjugative MDR pMG1-Like Plasmid Carrying theFrontiers in microbiology · 2021
    Article
  13. Molecular Characterization ofFrontiers in microbiology · 2021
    Article
  14. Review
  15. Article
  16. Antimicrobial Resistance inMicrobiology spectrum · 2018
    Review
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Hongbin SiCollege of Animal Sciences and Technology, Guangxi University, Nanning, China.
Wan-Jiang ZhangState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Shengbo ChuState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Xiu-Mei WangState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Lei DaiDepartment of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA.
Xin HuaState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Zhimin DongState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Stefan SchwarzInstitute of Farm Animal Genetics, Friedrich-Loeffler-Institut (FLI), Neustadt-Mariensee, Germany siguo_liu@hvri.ac.cn stefan.schwarz@fli.bund.de.
Siguo LiuState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China siguo_liu@hvri.ac.cn stefan.schwarz@fli.bund.de.
Chinese Academy of Agricultural Sciences · CNHarbin Veterinary Research Institute · CNFriedrich-Loeffler-Institut · DEGuangxi University · CNIowa State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel nonconjugative plasmid of 28,489 bp from a porcine linezolid-resistant Enterococcus faecium isolate was completely sequenced. This plasmid harbored a novel type of multiresistance gene cluster that comprised the resistance genes lnu(B), lsa(E), spw, aadE, aphA3, and two copies of erm(B), which account for resistance to macrolides, lincosamides, streptogramins, pleuromutilins, streptomycin, spectinomycin, and kanamycin/neomycin. Structural comparisons suggested that this plasmid might have developed from other enterococcal plasmids by insertion element (IS)-mediated interplasmid recombination processes.

Indexed as

AnimalsAnti-Bacterial AgentsDiterpenesDrug Resistance, Multiple, BacterialEnterococcus faeciumLincosamidesLinezolidMacrolidesMiceMicrobial Sensitivity TestsPlasmidsPleuromutilinsPolycyclic CompoundsStreptograminsSwineAnti-Bacterial AgentsDiterpenesLincosamidesLinezolidMacrolidesPleuromutilinsPolycyclic CompoundsStreptogramins

Identifiers

PMID26324271
PMCPMC4604366
OpenAlexW2160046377

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.