ArticleJournal of neuroengineering and rehabilitation2015
Detection of postural sway abnormalities by wireless inertial sensors in minimally disabled patients with multiple sclerosis: a case-control study.
Article in Journal of neuroengineering and rehabilitation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Wearable Inertial Sensors to Assess Standing Balance: A Systematic Review.Sensors (Basel, Switzerland) · 2019Pooled it
- Eyes closed single-leg stance test detects subtle sensorimotor decline in early multiple sclerosis.Scientific reports · 2026Article
- Optimizing noisy galvanic vestibular stimulation (nGVS) for postural control: methodological considerations when individualizing the signal for people with bilateral vestibulopathy.Frontiers in neurology · 2025Article
- Sample Entropy Improves Assessment of Postural Control in Early-Stage Multiple Sclerosis.Sensors (Basel, Switzerland) · 2024Article
- Assessing Free-Living Postural Sway in Persons With Multiple Sclerosis.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2024Article
- Inertial Measurement Unit-Based Romberg Test for Assessing Adults With Vestibular Hypofunction.IEEE journal of translational engineering in health and medicine · 2024Article
- Wearable Sensor Technologies to Assess Motor Functions in People With Multiple Sclerosis: Systematic Scoping Review and Perspective.Journal of medical Internet research · 2023Article
- Chest-Based Wearables and Individualized Distributions for Assessing Postural Sway in Persons With Multiple Sclerosis.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2023Article
- Balance Impairments in People with Early-Stage Multiple Sclerosis: Boosting the Integration of Instrumented Assessment in Clinical Practice.Sensors (Basel, Switzerland) · 2022Article
- Postural Sway in Parkinson's Disease and Multiple Sclerosis Patients During Tasks With Different Complexity.Frontiers in neurology · 2022Article
- APDM gait and balance measures fail to predict symptom progression rate in Parkinson's disease.Frontiers in neurology · 2022Article
- Review-Emerging Portable Technologies for Gait Analysis in Neurological Disorders.Frontiers in human neuroscience · 2022Review
- Article
- Using Machine Learning Algorithms for Identifying Gait Parameters Suitable to Evaluate Subtle Changes in Gait in People with Multiple Sclerosis.Brain sciences · 2021Article
- Design, Validity, and Reliability of a New Test, Based on an Inertial Measurement Unit System, for Measuring Cervical Posture and Motor Control in Children with Cerebral Palsy.Diagnostics (Basel, Switzerland) · 2020Article
- Fifteen Years of Wireless Sensors for Balance Assessment in Neurological Disorders.Sensors (Basel, Switzerland) · 2020Review
- Impact of Visual Biofeedback of Trunk Sway Smoothness on Motor Learning during Unipedal Stance.Sensors (Basel, Switzerland) · 2020Article
- Concurrent Validity and Reliability of an Inertial Measurement Unit for the Assessment of Craniocervical Range of Motion in Subjects with Cerebral Palsy.Diagnostics (Basel, Switzerland) · 2020Article
- Next Steps in Wearable Technology and Community Ambulation in Multiple Sclerosis.Current neurology and neuroscience reports · 2019Review
- Balance Changes in Patients With Relapsing-Remitting Multiple Sclerosis: A Pilot Study Comparing the Dynamics of the Relapse and Remitting Phases.Frontiers in neurology · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCommon clinical neurological exams can be insensitive to balance and mobility impairment at the early stages of multiple sclerosis (MS) and may not correspond with patient reports. Instrumented measurement of standing postural sway with inertial motion sensors may provide sensitive measures of balance impairment and better correspond with patient reports.
methodsWhile wearing wireless inertial sensors, 20 subjects with MS - Expanded Disability Status Scale of less than 3.0 and a Timed 25 Foot Walk of 5 sec or less - and 20 age- and sex-matched control subjects stood with eyes open and eyes closed on a foam surface. Forty-six outcome measures of postural sway were derived. A stepwise logistic regression model determined which measures of instrumented sway provide independent predictors of group status. Subjects with MS also completed the Activities-Specific Balance Confidence (ABC) scale and the 12-Item MS Walking Scale (MSWS-12) as measures of subject-reported balance and mobility impairment.
resultsThe regression model identified medio-lateral sway path length and medio-lateral range of sway acceleration amplitude, each in the eyes-open condition, as the only two significant independent predictors to differentiate subjects with MS from those without MS (model chi-squared = 34.55, p < 0.0001): accuracy = 87.5 %, positive likelihood ratio = 6 (2.09-17.21), negative likelihood ratio = 0.12 (0.03-0.44). Range of sway acceleration amplitude significantly correlated with both ABC (Spearman's r = -0.567, p = 0.009) and MSWS-12 scores (Spearman's r = -0.590, p = 0.006).
conclusionsPostural sway abnormalities in subjects with MS who are minimally disabled were detected using wireless inertial sensors and may signify a superior sensitivity to identify balance impairment prior to developing clinically evident disability or impaired gait speed. Further study is needed to confirm the clinical significance and predictive value of these objectively identified balance impairments.
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