Evidence map›Paper›PMID 26323754›Full record

ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2015

Eukaryotes first: how could that be?

Carlos Mariscal, W Ford Doolittle

Open access · bronzeAbstract readReview
In one paragraph

Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. The essence of life revisited: how theories can shed light on it.Theory in biosciences = Theorie in den Biowissenschaften · 2022
    Article
  4. The Evolution of the Hallmarks of Aging.Frontiers in genetics · 2021
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Changing ideas about eukaryotic origins.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Carlos MariscalDepartments of Philosophy, Dalhousie University, PO Box 15000, Halifax, Nova Scotia, Canada B3H 4R2 Biochemistry and Molecular Biology, Dalhousie University, PO Box 15000, Halifax, Nova Scotia, Canada B3H 4R2.
W Ford DoolittleBiochemistry and Molecular Biology, Dalhousie University, PO Box 15000, Halifax, Nova Scotia, Canada B3H 4R2 w.ford.doolittle@dal.ca.
Dalhousie University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the half century since the formulation of the prokaryote : eukaryote dichotomy, many authors have proposed that the former evolved from something resembling the latter, in defiance of common (and possibly common sense) views. In such 'eukaryotes first' (EF) scenarios, the last universal common ancestor is imagined to have possessed significantly many of the complex characteristics of contemporary eukaryotes, as relics of an earlier 'progenotic' period or RNA world. Bacteria and Archaea thus must have lost these complex features secondarily, through 'streamlining'. If the canonical three-domain tree in which Archaea and Eukarya are sisters is accepted, EF entails that Bacteria and Archaea are convergently prokaryotic. We ask what this means and how it might be tested.

Indexed as

Biological EvolutionEukaryotic CellsArchaeaBacteriaGenomeconvergenceeukaryotesLECALUCAstreamlining

Identifiers

PMID26323754
PMCPMC4571562
OpenAlexW2131993994

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.