Evidence map›Paper›PMID 26323714›Full record

ArticleBioinformatics (Oxford, England)2015

RNASeqMetaDB: a database and web server for navigating metadata of publicly available mouse RNA-Seq datasets.

Zhengyu Guo, Boriana Tzvetkova, Jennifer M Bassik, Tara Bodziak, Brianna M Wojnar, Wei Qiao, Md A Obaida, Sacha B Nelson, Bo Hua Hu, Peng Yu

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. SFMetaDB: a comprehensive annotation of mouse RNA splicing factor RNA-Seq datasets.Database : the journal of biological databases and curation · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhengyu GuoDepartment of Electrical and Computer Engineering & TEES-AgriLife Center for Bioinformatics and Genomic Systems Engineering, Texas A&M University, College Station, TX 77843, USA.
Boriana TzvetkovaDepartment of Biology & Center for Behavioral Genomics, Brandeis University, Waltham, MA 02454, USA and.
Jennifer M BassikDepartment of Communicative Disorders and Sciences & Center for Hearing and Deafness, University at Buffalo, Buffalo, NY 14214, USA.
Tara BodziakDepartment of Communicative Disorders and Sciences & Center for Hearing and Deafness, University at Buffalo, Buffalo, NY 14214, USA.
Brianna M WojnarDepartment of Communicative Disorders and Sciences & Center for Hearing and Deafness, University at Buffalo, Buffalo, NY 14214, USA.
Wei QiaoDepartment of Electrical and Computer Engineering &
Md A ObaidaDepartment of Electrical and Computer Engineering &
Sacha B NelsonDepartment of Biology & Center for Behavioral Genomics, Brandeis University, Waltham, MA 02454, USA and.
Bo Hua HuDepartment of Communicative Disorders and Sciences & Center for Hearing and Deafness, University at Buffalo, Buffalo, NY 14214, USA.
Peng YuDepartment of Electrical and Computer Engineering & TEES-AgriLife Center for Bioinformatics and Genomic Systems Engineering, Texas A&M University, College Station, TX 77843, USA.

Funding

Combining genetics, genomics, and anatomy to classify cell types across mammalsU01MH105949 · NIMH · BRANDEIS UNIVERSITY · PI BEJERANO, GILL, LOIS, CARLOS · 2014 to 2016
$3.4M
Noise-induced acute hair cell DeathR01DC010154 · NIDCD · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI HU, BO HUA · 2010 to 2014
$2.0M
A Database of Mammalian Neuronal Cell TypesR01NS075007 · NINDS · BRANDEIS UNIVERSITY · PI NELSON, SACHA B · 2012 to 2016
$1.8M
NIDCD NIH HHS R01 DC010154NIDCD NIH HHS R01DC010154NIMH NIH HHS U01 MH105949NINDS NIH HHS R01 NS075007
6 · The paper itself

Abstract

unlabelledGene targeting is a protocol for introducing a mutation to a specific gene in an organism. Because of the importance of in vivo assessment of gene function and modeling of human diseases, this technique has been widely adopted to generate a large number of mutant mouse models. Due to the recent breakthroughs in high-throughput sequencing technologies, RNA-Seq experiments have been performed on many of these mouse models, leading to hundreds of publicly available datasets. To facilitate the reuse of these datasets, we collected the associated metadata and organized them in a database called RNASeqMetaDB. The metadata were manually curated to ensure annotation consistency. We developed a web server to allow easy database navigation and data querying. Users can search the database using multiple parameters like genes, diseases, tissue types, keywords and associated publications in order to find datasets that match their interests. Summary statistics of the metadata are also presented on the web server showing interesting global patterns of RNA-Seq studies. AVAILABILITY AND IMPLEMENTATION: Freely available on the web at http://rnaseqmetadb.ece.tamu.edu.

Indexed as

Databases, Nucleic AcidSequence Analysis, RNASoftwareAnimalsHigh-Throughput Nucleotide SequencingMice

Identifiers

PMID26323714
PMCPMC4692969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.