ArticleILAR journal2015
The Mammalian Microbiome and Its Importance in Laboratory Animal Research.
Article in ILAR journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 37 citations in OpenAlex.
- Exploring the Development of Wild Microbiomes in the Eastern Fence Lizard.Environmental microbiology reports · 2026Article
- The prairie vole gut-brain-microbiota-axis: a narrative review.Gut microbiome (Cambridge, England) · 2026Review
- FELASA-AALAS Recommendations for Biosecurity in an Aquatic Facility, Including Prevention of Zoonosis, Introduction of New Fish Colonies, and Quarantine.Comparative medicine · 2022Article
- Peptidoglycan of Bacterial Cell Wall Affects Competitive Properties of Microorganisms.Bulletin of experimental biology and medicine · 2021Article
- Effect of Housing Condition and Diet on the Gut Microbiota of Weanling Immunocompromised Mice.Comparative medicine · 2021Article
- Metaplasmidome-encoded functions of Siberian low-centered polygonal tundra soils.The ISME journal · 2021Article
- Health Monitoring of Laboratory Rodent Colonies-Talking about (R)evolution.Animals : an open access journal from MDPI · 2021Review
- Impact of the repurposed drug thonzonium bromide on host oral-gut microbiomes.NPJ biofilms and microbiomes · 2021Article
- Association of a dysbiotic oral microbiota with the development of focal lymphocytic sialadenitis in IκB-ζ-deficient mice.NPJ biofilms and microbiomes · 2020Article
- Large-scale metabolic interaction network of the mouse and human gut microbiota.Scientific data · 2020Article
- The development of colitis in Il10Mucosal immunology · 2020Article
- Microbiota Alters Urinary Bladder Weight and Gene Expression.Microorganisms · 2020Article
- Current Distribution ofJournal of the American Association for Laboratory Animal Science : JAALAS · 2019Article
- Composition of the Intestinal Microbiota Determines the Outcome of Virus-Triggered Colitis in Mice.Frontiers in immunology · 2019Article
- Escherichia coli NGF-1, a Genetically Tractable, Efficiently Colonizing Murine Gut Isolate.Microbiology resource announcements · 2018Article
- Gnotobiotic and Conventional Mouse Systems to Support Microbiota Based Studies.Current protocols in immunology · 2018Article
- Immune responses to the real world.Lab animal · 2017Article
- Chemically induced mouse models of acute and chronic intestinal inflammation.Nature protocols · 2017Article
- The role of the IACUC in ensuring research reproducibility.Lab animal · 2017Review
- Antimicrobial Stewardship in Laboratory Animal Facilities.Journal of the American Association for Laboratory Animal Science : JAALAS · 2017Article
Corrections and comments
- Erratum issuedErratum.2016
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In this issue are assembled 10 fascinating, well-researched papers that describe the emerging field centered on the microbiome of vertebrate animals and how these complex microbial populations play a fundamental role in shaping homeostasis of the host. The content of the papers will deal with bacteria and, because of relative paucity of information on these organisms, will not include discussions on viruses, fungus, protozoa, and parasites that colonize various animals. Dissecting the number and interactions of the 500-1000 bacterial species that can inhabit the intestines of animals is made possible by advanced DNA sequencing methods, which do not depend on whether the organism can be cultured or not. Laboratory animals, particularly rodents, have proven to be an indispensable component in not only understanding how the microbiome aids in digestion and protects the host against pathogens, but also in understanding the relationship of various species of bacteria to development of the immune system. Importantly, this research elucidates purported mechanisms for how the microbiome can profoundly affect initiation and progression of diseases such as type 1 diabetes, metabolic syndromes, obesity, autoimmune arthritis, inflammatory bowel disease, and irritable bowel syndrome. The strengths and limitations of the use of germfree mice colonized with single species of bacteria, a restricted flora, or most recently the use of human-derived microbiota are also discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.