Evidence map›Paper›PMID 26322638›Full record

ArticlePloS one2015

Phase-Contrast Hounsfield Units of Fixated and Non-Fixated Soft-Tissue Samples.

Marian Willner, Gabriel Fior, Mathias Marschner, Lorenz Birnbacher, Jonathan Schock, Christian Braun, Alexander A Fingerle, Peter B Noël, Ernst J Rummeny, Franz Pfeiffer and 1 more

Abstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Does formalin fixation influence MSCT/CBCT accuracy?Surgical and radiologic anatomy : SRA · 2018
    Article
  11. Article
  12. Article
  13. ACS biomaterials science & engineering · 2016
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marian WillnerDepartment of Physics & Institute of Medical Engineering, Technische Universität München, Garching, Germany.
Gabriel FiorDepartment of Physics & Institute of Medical Engineering, Technische Universität München, Garching, Germany.
Mathias MarschnerDepartment of Physics & Institute of Medical Engineering, Technische Universität München, Garching, Germany.
Lorenz BirnbacherDepartment of Physics & Institute of Medical Engineering, Technische Universität München, Garching, Germany.
Jonathan SchockDepartment of Physics & Institute of Medical Engineering, Technische Universität München, Garching, Germany.
Christian BraunInstitute of Forensic Medicine, Ludwig-Maximilians-Universität, Munich, Germany.
Alexander A FingerleDepartment of Diagnostic and Interventional Radiology, Technische Universität München, Munich, Germany.
Peter B NoëlDepartment of Diagnostic and Interventional Radiology, Technische Universität München, Munich, Germany.
Ernst J RummenyDepartment of Diagnostic and Interventional Radiology, Technische Universität München, Munich, Germany.
Franz PfeifferDepartment of Physics & Institute of Medical Engineering, Technische Universität München, Garching, Germany.
Julia HerzenDepartment of Physics & Institute of Medical Engineering, Technische Universität München, Garching, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

X-ray phase-contrast imaging is a novel technology that achieves high soft-tissue contrast. Although its clinical impact is still under investigation, the technique may potentially improve clinical diagnostics. In conventional attenuation-based X-ray computed tomography, radiological diagnostics are quantified by Hounsfield units. Corresponding Hounsfield units for phase-contrast imaging have been recently introduced, enabling a setup-independent comparison and standardized interpretation of imaging results. Thus far, the experimental values of few tissue types have been reported; these values have been determined from fixated tissue samples. This study presents phase-contrast Hounsfield units for various types of non-fixated human soft tissues. A large variety of tissue specimens ranging from adipose, muscle and connective tissues to liver, kidney and pancreas tissues were imaged by a grating interferometer with a rotating-anode X-ray tube and a photon-counting detector. Furthermore, we investigated the effects of formalin fixation on the quantitative phase-contrast imaging results.

Indexed as

Connective TissueHumansKidneyLiverMicroscopy, Phase-ContrastMusclesPancreasPhotonsTomography, X-Ray ComputedX-Ray Diffraction

Identifiers

PMID26322638
PMCPMC4556454

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.