Evidence map›Paper›PMID 26322277›Full record

ReviewFrontiers in cellular and infection microbiology2015

Opening the black box of Anaplasma phagocytophilum diversity: current situation and future perspectives.

Thibaud Dugat, Anne-Claire Lagrée, Renaud Maillard, Henri-Jean Boulouis, Nadia Haddad

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed.

  1. Pathogens (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Coinfection ecology and pathogen emergence in aApplied and environmental microbiology · 2026
    Article
  4. mBio · 2026
    Article
  5. Article
  6. Molecular detection and phylogenetic characterization ofFrontiers in cellular and infection microbiology · 2026
    Article
  7. Article
  8. Exploration of geographical population structure ofCurrent research in parasitology & vector-borne diseases · 2026
    Article
  9. Coinfection Ecology and Pathogen Emergence in amedRxiv : the preprint server for health sciences · 2025
    Article
  10. Article
  11. Article
  12. Current research in parasitology & vector-borne diseases · 2025
    Article
  13. Article
  14. Article
  15. Tick-Borne Bacterial Diseases in Europe: Threats to public health.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Review
  16. Article
  17. Microorganisms · 2024
    Article
  18. Diversity ofAnimals : an open access journal from MDPI · 2024
    Article
  19. Article
  20. Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thibaud DugatLaboratoire de Santé Animale, UMR Biologie Moléculaire et Immunologie Parasitaires, Agence Nationale de Sécurité Sanitaire de L'alimentation, de L'environnement et du Travail, Université Paris-Est Paris, France.
Anne-Claire LagréeUMR Biologie Moléculaire et Immunologie Parasitaires, Ecole Nationale Vétérinaire d'Alfort, Université Paris-Est Paris, France.
Renaud MaillardUMR Biologie Moléculaire et Immunologie Parasitaires, Ecole Nationale Vétérinaire d'Alfort, Université Paris-Est Paris, France ; Unité Pathologie des Ruminants, Ecole Nationale Vétérinaire de Toulouse Toulouse, France.
Henri-Jean BoulouisUMR Biologie Moléculaire et Immunologie Parasitaires, Ecole Nationale Vétérinaire d'Alfort, Université Paris-Est Paris, France.
Nadia HaddadUMR Biologie Moléculaire et Immunologie Parasitaires, Ecole Nationale Vétérinaire d'Alfort, Université Paris-Est Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anaplasma phagocytophilum is a zoonotic obligate intracellular bacterium known to be transmitted by ticks belonging to the Ixodes persulcatus complex. This bacterium can infect several mammalian species, and is known to cause diseases with variable symptoms in many domestic animals. Specifically, it is the causative agent of tick-borne fever (TBF), a disease of important economic impact in European domestic ruminants, and human granulocytic anaplasmosis (HGA), an emerging zoonotic disease in Asia, USA and Europe. A. phagocytophilum epidemiological cycles are complex and involve different ecotypes, vectors, and mammalian host species. Moreover, the epidemiology of A. phagocytophilum infection differs greatly between Europe and the USA. These different epidemiological contexts are associated with considerable variations in bacterial strains. Until recently, few A. phagocytophilum molecular typing tools were available, generating difficulties in completely elucidating the epidemiological cycles of this bacterium. Over the last few years, many A. phagocytophilum typing techniques have been developed, permitting in-depth epidemiological exploration. Here, we review the current knowledge and future perspectives regarding A. phagocytophilum epidemiology and phylogeny, and then focus on the molecular typing tools available for studying A. phagocytophilum genetic diversity.

Indexed as

Genetic VariationMolecular TypingPhylogenyAnaplasma phagocytophilumAnaplasmosisAnimalsAsiaEuropeHumansIxodesMolecular EpidemiologyUnited StatesAnaplasma phagocytophilumdiversityepidemiologygranulocytic anaplasmosisphylogenytick-borne fevertyping technique

Identifiers

PMID26322277
PMCPMC4536383

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.