Evidence map›Paper›PMID 26322247›Full record

ArticleIEEE transactions on terahertz science and technology2015

THz and mm-Wave Sensing of Corneal Tissue Water Content: Electromagnetic Modeling and Analysis.

Zachary D Taylor, James Garritano, Shijun Sung, Neha Bajwa, David B Bennett, Bryan Nowroozi, Priyamvada Tewari, James Sayre, Jean-Pierre Hubschman, Sophie Deng and 2 more

Abstract read
In one paragraph

Article in IEEE transactions on terahertz science and technology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

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  10. Triage ofBiomedical optics express · 2023
    Article
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  12. Corneal stromal dehydration and optimal stromal exposure time during corneal refractive surgery measured using a three-dimensional optical profiler.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
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  18. 650 GHz imaging as alignment verification for millimeter wave corneal reflectometry.IEEE transactions on terahertz science and technology · 2022
    Article
  19. Photocurable GelMA Adhesives for Corneal Perforations.Bioengineering (Basel, Switzerland) · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zachary D TaylorDepartment of Bioengineering, University of California (UCLA), Los Angeles, CA 90095 USA, and also with the Center for Advanced Surgical and Interventional Technology (CASIT), University of California (UCLA), Los Angeles, CA 90095 USA.
James GarritanoDepartment of Bioengineering, University of California (UCLA), Los Angeles, CA 90095 USA, and also with the Center for Advanced Surgical and Interventional Technology (CASIT), University of California (UCLA), Los Angeles, CA 90095 USA.
Shijun SungDepartment of Electrical Engineering, University of California (UCLA), Los Angeles, CA 90095 USA.
Neha BajwaDepartment of Bioengineering, University of California (UCLA), Los Angeles, CA 90095 USA, and also with the Center for Advanced Surgical and Interventional Technology (CASIT), University of California (UCLA), Los Angeles, CA 90095 USA.
David B BennettDepartment of Electrical Engineering, University of California (UCLA), Los Angeles, CA 90095 USA. He is now with Fitbit, San Francisco, CA 94105 USA.
Bryan NowrooziDepartment of Bioengineering, University of California (UCLA), Los Angeles, CA 90095 USA, and also with the Center for Advanced Surgical and Interventional Technology (CASIT), University of California (UCLA), Los Angeles, CA 90095 USA. He is now with Mimeo Labs Inc, Santa Monica, CA 90404 USA.
Priyamvada TewariDepartment of Bioengineering, University of California (UCLA), Los Angeles, CA 90095 USA, and also with the Center for Advanced Surgical and Interventional Technology (CASIT), University of California (UCLA), Los Angeles, CA 90095 USA. She is now with Elsevier Life Science solutions, San Francisco, CA 94105 USA.
James SayreDepartment of Biostatistics, University of California (UCLA), Los Angeles, CA 90095 USA.
Jean-Pierre HubschmanDepartment of Ophthalmology, University of California (UCLA), Los Angeles, CA 90095 USA.
Sophie DengDepartment of Ophthalmology, University of California (UCLA), Los Angeles, CA 90095 USA.
Elliott R BrownDepartment. of Electrical Engineering, Wright State University, Dayton, OH 45435 USA.
Warren S GrundfestDepartment of Bioengineering, University of California (UCLA), Los Angeles, CA 90095 USA, and also with the Center for Advanced Surgical and Interventional Technology (CASIT), University of California (UCLA), Los Angeles, CA 90095 USA.

Funding

Non-Contact, THz Sensing of Corneal HydrationR01EY021590 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GRUNDFEST, WARREN S · 2011 to 2015
$1.9M
A Correlational Study of THz and MRI Hydration Mapping in In vivo Skin BurnsR21EB016896 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GRUNDFEST, WARREN S · 2014 to 2015
$407k
THz imaging of acute burn woundsR21EB015084 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GRUNDFEST, WARREN S · 2013 to 2014
$391k
NEI NIH HHS R01 EY021590NIBIB NIH HHS R21 EB015084NIBIB NIH HHS R21 EB016896
6 · The paper itself

Abstract

Terahertz (THz) spectral properties of human cornea are explored as a function of central corneal thickness (CCT) and corneal water content, and the clinical utility of THz-based corneal water content sensing is discussed. Three candidate corneal tissue water content (CTWC) perturbations, based on corneal physiology, are investigated that affect the axial water distribution and total thickness. The THz frequency reflectivity properties of the three CTWC perturbations were simulated and explored with varying system center frequency and bandwidths (Q-factors). The modeling showed that at effective optical path lengths on the order of a wavelength the cornea presents a lossy etalon bordered by air at the anterior and the aqueous humor at the posterior. The simulated standing wave peak-to-valley ratio is pronounced at lower frequencies and its effect on acquired data can be modulated by adjusting the bandwidth of the sensing system. These observations are supported with experimental spectroscopic data. The results suggest that

Indexed as

Biological and medical imagingclinical instrumentshydration interactionsmedical diagnostics

Identifiers

PMID26322247
PMCPMC4551413

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.