Evidence map›Paper›PMID 26322229›Full record

ArticleJournal of global health2015

Investments in sexually transmitted infection research, 1997-2013: a systematic analysis of funding awarded to UK institutions.

Michael G Head, Joseph R Fitchett, Jackie A Cassell, Rifat Atun

Abstract read
In one paragraph

Article in Journal of global health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Michael G HeadUniversity College London, Farr Institute for Health Informatics, London, UK.
Joseph R FitchettLondon School of Hygiene & Tropical Medicine, Department of Clinical Research, Keppel Street, London, UK ; Harvard School of Public Health, Harvard University, Boston, USA.
Jackie A CassellDivision of Primary Care and Public Health, Brighton and Sussex Medical School, Brighton, UK.
Rifat AtunHarvard School of Public Health, Harvard University, Boston, USA.

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundWe report the first study that analyses public and philanthropic investments awarded to UK institutions for research related to sexually transmitted infections (STIs).

methodsWe systematically searched award data from the major funders for information on all infectious disease research funding awarded in 1997-2013. The STI-related projects were identified and categorised by pathogen, disease and type of science along the research pipeline from preclinical to translational research.

findingsWe identified 7393 infection-related awards with total investment of GBP 3.5 billion. Of these, 1238 awards (16.7%) covering funding of GBP 719.1 million (20.5%) were for STI research. HIV as an STI received GBP 465 million across 719 studies; non-HIV STIs received GBP 139 million across 378 studies. The Medical Research Council provided greatest investment (GBP 193 million for HIV, GBP 45 million for non-HIV STIs). Preclinical awards totalled GBP 233 million (37.1%), whilst translational research received GBP 286 million (39.7%). Substantial proportions of HIV investment addressed global health research (GBP 265 million), vaccinology (GBP 110 million) and therapeutics (GBP 202 million). For other STIs, investments focused on diagnostics (GBP 45 million) and global health (GBP 27 million). Human Papilloma Virus research received GBP 58 million and chlamydia GBP 24 million. Funding for non-HIV STIs has declined in the three most recent years of this data set.

conclusionsThe investment for HIV research awarded to UK institutions correlates with the high global burden, but other STIs are relatively neglected, including gonorrhoea and syphilis. Future STI funding should be better aligned with burden while addressing the emerging risk of antimicrobial resistance in Neisseria gonorrhoeae and outbreaks of other pathogens.

Identifiers

PMID26322229
PMCPMC4544235

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