Evidence map›Paper›PMID 26321906›Full record

ArticleFrontiers in neuroscience2015

Lack of spatial segregation in the representation of pheromones and kairomones in the mouse medial amygdala.

Vinicius M A Carvalho, Thiago S Nakahara, Leonardo M Cardozo, Mateus A A Souza, Antonio P Camargo, Guilherme Z Trintinalia, Eliana Ferraz, Fabio Papes

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Vinicius M A CarvalhoDepartment of Genetics and Evolution, Institute of Biology, University of Campinas Campinas, Brazil ; Graduate Program in Genetics and Molecular Biology, Institute of Biology, University of Campinas Campinas, Brazil.
Thiago S NakaharaDepartment of Genetics and Evolution, Institute of Biology, University of Campinas Campinas, Brazil ; Graduate Program in Genetics and Molecular Biology, Institute of Biology, University of Campinas Campinas, Brazil.
Leonardo M CardozoDepartment of Genetics and Evolution, Institute of Biology, University of Campinas Campinas, Brazil ; Graduate Program in Genetics and Molecular Biology, Institute of Biology, University of Campinas Campinas, Brazil.
Mateus A A SouzaDepartment of Genetics and Evolution, Institute of Biology, University of Campinas Campinas, Brazil ; Graduate Program in Genetics and Molecular Biology, Institute of Biology, University of Campinas Campinas, Brazil.
Antonio P CamargoDepartment of Genetics and Evolution, Institute of Biology, University of Campinas Campinas, Brazil ; Undergraduate Program in the Biological Sciences, Institute of Biology, University of Campinas Campinas, Brazil.
Guilherme Z TrintinaliaDepartment of Genetics and Evolution, Institute of Biology, University of Campinas Campinas, Brazil ; Graduate Program in Genetics and Molecular Biology, Institute of Biology, University of Campinas Campinas, Brazil.
Eliana FerrazCampinas Municipal Zoo Campinas, Brazil.
Fabio PapesDepartment of Genetics and Evolution, Institute of Biology, University of Campinas Campinas, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nervous system is organized to detect, internally represent and process sensory information to generate appropriate behaviors. Despite the crucial importance of odors that elicit instinctive behaviors, such as pheromones and kairomones, their neural representation remains little characterized in the mammalian brain. Here we used expression of the immediate early gene product c-Fos as a marker of neuronal activity to find that a wide range of pheromones and kairomones produces activation in the medial nucleus of the amygdala, a brain area anatomically connected with the olfactory sensory organs. We see that activity in this nucleus depends on vomeronasal organ input, and that distinct vomeronasal stimuli activate a dispersed ensemble of cells, without any apparent spatial segregation. This activity pattern does not reflect the chemical category of the stimuli, their valence or the induced behaviors. These findings will help build a complete understanding of how odor information is processed in the brain to generate instinctive behaviors.

Indexed as

amygdalahigher-order representationkairomoneolfactionpheromonevomeronasal organ

Identifiers

PMID26321906
PMCPMC4531233
OpenAlexW1774188767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.