Evidence map›Paper›PMID 26321691›Full record

ReviewClinical therapeutics2015

Comanagement of Pediatric Depression and Obesity: A Clear Need for Evidence.

Nicole L Mihalopoulos, Michael G Spigarelli

Open access · greenAbstract readReview
In one paragraph

Review in Clinical therapeutics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nicole L MihalopoulosDivision of Adolescent Medicine, University of Utah, Salt Lake City, Utah.
Michael G SpigarelliDivision of Adolescent Medicine, University of Utah, Salt Lake City, Utah; Department of Clinical Pharmacology, University of Utah, Salt Lake City, Utah.. Electronic address: clinicaltherapeuticspeds@gmail.com.
University of Utah · US

Funding

Changes in Adipokines and Adiposity during Puberty and Young AdulthoodK23HL092069 · NHLBI · UNIVERSITY OF UTAH · PI MIHALOPOULOS, NICOLE LENORE · 2010 to 2014
$713k
NHLBI NIH HHS HL092069NHLBI NIH HHS K23 HL092069
6 · The paper itself

Abstract

purposeThe purpose of this article is to provide a review of the existing literature for the comanagement of depression and obesity in the pediatric population.

methodsA review of the current literature was conducted using EBSCOhost and EMBASE to identify evidence and recommendations for the comanagement of depression and obesity among children and adolescents (aged 2-18 years). Additional search criteria included peer-reviewed, English language-only full-text articles published before August 2015.

findingsMultiple factors contribute to and influence the interplay of obesity and depression in the pediatric population. These 2 chronic conditions are affected by multiple factors, including the roles of the family, school, health care practitioners, and access to health care. In addition, there are no formal recommendations for the treatment of depression in the setting of obesity for pediatric or adult populations, and there is only medication approved by the Food and Drug Administration (orlistat) for the treatment of obesity in the adolescent population. Bariatric surgery may play a role in some adolescents, but larger and long-term clinical studies with the use of therapeutic agents in conjunction with lifestyle modification need to be conducted to support this. IMPLICATIONS: The interrelatedness of these 2 separate diseases is not well understood; the presence of 1 of the diseases clearly contributes to the manifestation of the other and likely to the ability to treat the other disease. Current focus is on modifying behavior to decrease weight. Weight loss is associated with improvement in depressive symptoms but may not be adequate to treat depression.

Indexed as

AdolescentChildChild, PreschoolDepressionDisease ManagementEvidence-Based MedicineHumansLife StyleObesitydepressionmanagementobesitypediatrics

Identifiers

PMID26321691
PMCPMC4607257
OpenAlexW2108141937

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.