Drug delivery to chondrocytes.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

18 citing papers in PubMed.

1. Cyclodextrin-Epichlorohydrin-Cyanoguanidine Polymer for Resveratrol Delivery to Enhance Human Chondrocyte Function in Cartilage Repair.Biomacromolecules · 2026
   Article
2. Microfluidic Nanocomposite Lubricating Microgels Localized Deliver Celastrol for Remodeling the Immune Microenvironment to Enhance Osteoarthritis Treatment.Research (Washington, D.C.) · 2026
   Article
3. The osteoarthritis inflammatory ecosystem: a node-edge-boundary-emergent framework toward precision stratification and therapeutic hypothesis generation.Frontiers in medicine · 2026
   Review
4. Rethinking Osteoarthritis Management: Synergistic Effects of Chronoexercise, Circadian Rhythm, and Chondroprotective Agents.Biomedicines · 2025
   Article
5. Advancing drug delivery to articular cartilage: From single to multiple strategies.Acta pharmaceutica Sinica. B · 2023
   Review
6. Articular fibrocartilage-targeted therapy by microtubule stabilization.Science advances · 2022
   Article
7. Microcarriers in application for cartilage tissue engineering: Recent progress and challenges.Bioactive materials · 2022
   Review
8. Chondrocyte-specific genomic editing enabled by hybrid exosomes for osteoarthritis treatment.Theranostics · 2022
   Article
9. Poly beta amino ester coated emulsions of NSAIDs for cartilage treatment.Journal of materials chemistry. B · 2021
   Article
10. Oligonucleotide Therapies in the Treatment of Arthritis: A Narrative Review.Biomedicines · 2021
    Review
11. Multi-arm Avidin nano-construct for intra-cartilage delivery of small molecule drugs.Journal of controlled release : official journal of the Controlled Release Society · 2020
    Article
12. Interleukin-1 receptor antagonist (IL-1Ra) is more effective in suppressing cytokine-induced catabolism in cartilage-synovium co-culture than in cartilage monoculture.Arthritis research & therapy · 2019
    Article
13. Cartilage penetrating cationic peptide carriers for applications in drug delivery to avascular negatively charged tissues.Acta biomaterialia · 2019
    Article
14. Molecular transport in articular cartilage - what have we learned from the past 50 years?Nature reviews. Rheumatology · 2018
    Review
15. Sustained intra-cartilage delivery of low dose dexamethasone using a cationic carrier for treatment of post traumatic osteoarthritis.European cells & materials · 2017
    Article
16. Cartilage-targeting drug delivery: can electrostatic interactions help?Nature reviews. Rheumatology · 2017
    Review
17. Poly-beta-amino-esters nano-vehicles based drug delivery system for cartilage.Nanomedicine : nanotechnology, biology, and medicine · 2017
    Article
18. Controlled Release of Interleukin-1 Receptor Antagonist from Hyaluronic Acid-Chitosan Microspheres Attenuates Interleukin-1BioMed research international · 2016
    Article

Corrections and comments

• Comment on
  Charge based intra-cartilage delivery of single dose dexamethasone using Avidin nano-carriers suppresses cytokine-induced catabolism long term.2016

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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