ArticleJournal of extracellular vesicles2015
Integration of extracellular RNA profiling data using metadata, biomedical ontologies and Linked Data technologies.
Article in Journal of extracellular vesicles, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Real-time, automated, standardized, and transparent analysis of microfluidic nanoparticle data with RPSbioRxiv : the preprint server for biology · 2026Article
- Selected miRNAs in Urinary Extracellular Vesicles Show Promise for Early and Specific Diagnostics of Diabetic Kidney Disease.Journal of extracellular biology · 2025Article
- Host-dependent alteration of the gut microbiota: the role of luminal microRNAs.Microbiome research reports · 2025Review
- International Society for Extracellular Vesicles Workshop. QuantitatEVs: multiscale analyses, from bulk to single extracellular vesicle.Journal of extracellular biology · 2024Article
- Ultrasensitive Protein Detection Technologies for Extracellular Vesicle Measurements.Molecular & cellular proteomics : MCP · 2023Article
- Emerging Roles of Mesenchymal Stem/Stromal-Cell-Derived Extracellular Vesicles in Cancer Therapy.Pharmaceutics · 2023Review
- exRNA-eCLIP intersection analysis reveals a map of extracellular RNA binding proteins and associated RNAs across major human biofluids and carriers.Cell genomics · 2023Article
- Quality Management Tools on the Stage: Old but New Allies for Rigor and Standardization of Extracellular Vesicle Studies.Frontiers in bioengineering and biotechnology · 2022Article
- Longitudinal saliva omics responses to immune perturbation: a case study.Scientific reports · 2021Article
- Open Problems in Extracellular RNA Data Analysis: Insights From an ERCC Online Workshop.Frontiers in genetics · 2021Article
- Exosomal microRNAs are novel circulating biomarkers in cigarette, waterpipe smokers, E-cigarette users and dual smokers.BMC medical genomics · 2020Article
- Discovery and Verification of Extracellular miRNA Biomarkers for Non-invasive Prediction of Pre-eclampsia in Asymptomatic Women.Cell reports. Medicine · 2020Article
- COMPSRA: a COMprehensive Platform for Small RNA-Seq data Analysis.Scientific reports · 2020Article
- Article
- Circulating miRNAs and Risk of Sudden Death in Patients With Coronary Heart Disease.JACC. Clinical electrophysiology · 2020Article
- Oral Administration of miR-30d from Feces of MS Patients Suppresses MS-like Symptoms in Mice by Expanding Akkermansia muciniphila.Cell host & microbe · 2019Article
- Predicting instances of pathway ontology classes for pathway integration.Journal of biomedical semantics · 2019Article
- The Effects of Regular Exercise on Circulating Cardiovascular-related MicroRNAs.Scientific reports · 2019Article
- exceRpt: A Comprehensive Analytic Platform for Extracellular RNA Profiling.Cell systems · 2019Article
- Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
The large diversity and volume of extracellular RNA (exRNA) data that will form the basis of the exRNA Atlas generated by the Extracellular RNA Communication Consortium pose a substantial data integration challenge. We here present the strategy that is being implemented by the exRNA Data Management and Resource Repository, which employs metadata, biomedical ontologies and Linked Data technologies, such as Resource Description Framework to integrate a diverse set of exRNA profiles into an exRNA Atlas and enable integrative exRNA analysis. We focus on the following three specific data integration tasks: (a) selection of samples from a virtual biorepository for exRNA profiling and for inclusion in the exRNA Atlas; (b) retrieval of a data slice from the exRNA Atlas for integrative analysis and (c) interpretation of exRNA analysis results in the context of pathways and networks. As exRNA profiling gains wide adoption in the research community, we anticipate that the strategies discussed here will increasingly be required to enable data reuse and to facilitate integrative analysis of exRNA data.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.