Observational studyDigestive diseases and sciences2016
Correlation Between Capillary and Venous Blood Glucose in the Lactose Tolerance Test.
Observational study in Digestive diseases and sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Can isometric testing substitute for the one repetition maximum squat test?European journal of applied physiology · 2024Article
- Maximal strength measurement: A critical evaluation of common methods-a narrative review.Frontiers in sports and active living · 2023Review
- Review
- Lactose tolerance test as an alternative to hydrogen breath test in the study of lactose malabsorption.Advances in laboratory medicine · 2020Article
- Update on lactose malabsorption and intolerance: pathogenesis, diagnosis and clinical management.Gut · 2019Review
- [Lactose Malabsorption and Intolerance].Acta gastroenterologica LatinoamericanaReview
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
backgroundThe lactose tolerance test is a classic method for the study of lactose malabsorption. However, the methodology used has not been standardized, and this leads to differences in results.
aimThe aim of this report was to analyze whether capillary blood glucose measurement is in agreement with venous blood glucose when performing lactose tolerance test.
methodsThis is a prospective study of consecutive patients with suspected lactose malabsorption who had lactose tolerance test performed in venous and capillary blood simultaneously, using a load of 50 g lactose. Agreement was measured using the concordance correlation coefficient of Lin (95 % CI) and Bland-Altman plots. The degree of agreement was measured using the Kappa index. A value of p < 0.05 was considered statistically significant.
resultsEighty-four patients (68 % women) were included. The concordance correlation coefficient showed very poor agreement between the two techniques: 0.68 (0.58-0.77), 0.72 (0.62-0.8), and 0.77 (0.69-0.83) for baseline, 30, and 60 min, respectively. The Bland-Altman plots showed that capillary blood glucose measurements result in higher levels than venous blood glucose measurements, with mean differences of 0.39, 0.77, and 1.1 mmol/L at baseline, 30, and 60 min, respectively. The degree of agreement was low, with a Kappa index of 0.59 (p < 0.001).
conclusionsThe test measured in venous blood is not in agreement with the measurement obtained from capillary blood. It is likely that the diagnostic accuracy attributed without distinction to lactose tolerance test in different studies for lactose malabsorption is incorrect, making it necessary to specify the analysis method.
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