ArticleGenome biology2015
Predicting the spatial organization of chromosomes using epigenetic data.
Article in Genome biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- H3K36 Methylation as a Guardian of Epigenome Integrity.Nature communications · 2025Article
- Article
- Interplay between epigenome and 3D chromatin structure.BMB reports · 2023Review
- Genome-wide analysis of the interplay between chromatin-associated RNA and 3D genome organization in human cells.Nature communications · 2023Article
- Decoding the spatial chromatin organization and dynamic epigenetic landscapes of macrophage cells during differentiation and immune activation.Nature communications · 2022Article
- Chromatin Interaction Responds to Breast Muscle Development and Intramuscular Fat Deposition Between Chinese Indigenous Chicken and Fast-Growing Broiler.Frontiers in cell and developmental biology · 2021Article
- Review
- Automatic detection of genomic regions with informative epigenetic patterns.BMC genomics · 2018Article
- From 1D sequence to 3D chromatin dynamics and cellular functions: a phase separation perspective.Nucleic acids research · 2018Article
- An epigenetic association of malformations, adverse reproductive outcomes, and fetal origins hypothesis related effects.Journal of assisted reproduction and genetics · 2018Review
- Computational characterization of chromatin domain boundary-associated genomic elements.Nucleic acids research · 2017Article
- Uncovering direct and indirect molecular determinants of chromatin loops using a computational integrative approach.PLoS computational biology · 2017Article
- 3DSNP: a database for linking human noncoding SNPs to their three-dimensional interacting genes.Nucleic acids research · 2017Article
- Cajal body function in genome organization and transcriptome diversity.BioEssays : news and reviews in molecular, cellular and developmental biology · 2016Review
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chromosome folding can reinforce the demarcation between euchromatin and heterochromatin. Two new studies show how epigenetic data, including DNA methylation, can accurately predict chromosome folding in three dimensions. Such computational approaches reinforce the idea of a linkage between epigenetically marked chromatin domains and their segregation into distinct compartments at the megabase scale or topological domains at a higher resolution. Please see related articles: http://dx.doi.org/10.1186/s13059-015-0741-y and http://dx.doi.org/10.1186/s13059-015-0740-z.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.