ArticleCurrent microbiology2015
Porcine Epidemic Diarrhea Virus Infection Induced the Unbalance of Gut Microbiota in Piglets.
Article in Current microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 56 citations in OpenAlex.
- Astrovirus infection alters gut microbial communities in a widespread neotropical bat across human-modified landscapes.BMC microbiology · 2026Article
- Multi-omics analysis reveals that glyceryl monooleate mitigates PEDV-induced intestinal injury in piglets.BMC microbiology · 2026Article
- Intestinal microbiota dynamics in piglets: the interplay with swine enteric coronavirus infections and implications for disease control.Animal microbiome · 2025Review
- Application of mRNA-Seq and Metagenomic Sequencing to StudyInternational journal of molecular sciences · 2025Article
- Determinants of piglet gut microbiome colonization: roles of genetics, nutrition, therapeutics, and the impact of enteric pathogens like PEDV.Frontiers in cellular and infection microbiology · 2025Review
- 16S rDNA sequencing combined with metabolomic probes to investigate the effects ofFrontiers in microbiology · 2025Article
- The Impact ofPathogens (Basel, Switzerland) · 2024Article
- Comparative analysis of fecal microbiota between diarrhea and non-diarrhea piglets reveals biomarkers of gut microbiota associated with diarrhea.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- Swine Colibacillosis: Analysis of the Gut Bacterial Microbiome.Microorganisms · 2024Article
- Combining 16S rRNA Sequencing and Metabolomics Data to Decipher the Interactions between Gut Microbiota, Host Immunity, and Metabolites in Diarrheic Young Small Ruminants.International journal of molecular sciences · 2023Article
- Mini-review: microbiota have potential to prevent PEDV infection by improved intestinal barrier.Frontiers in immunology · 2023Review
- An insight into the commercial piglet's microbial gut colonization: from birth towards weaning.Animal microbiome · 2022Article
- Rotavirus Infection in Swine: Genotypic Diversity, Immune Responses, and Role of Gut Microbiome in Rotavirus Immunity.Pathogens (Basel, Switzerland) · 2022Review
- ADDAGMA: A database for domestic animal gut microbiome atlas.Computational and structural biotechnology journal · 2022Article
- Difference analysis of intestinal microbiota and metabolites in piglets of different breeds exposed to porcine epidemic diarrhea virus infection.Frontiers in microbiology · 2022Article
- Characterization of Bacterial Microbiota Composition in Healthy and Diarrheal Early-Weaned Tibetan Piglets.Frontiers in veterinary science · 2022Article
- Understanding host-microbiota interactions in the commercial piglet around weaning.Scientific reports · 2021Article
- Emodin Improves Intestinal Health and Immunity through Modulation of Gut Microbiota in Mice Infected by PathogenicAnimals : an open access journal from MDPI · 2021Article
- Early socialization and environmental enrichment of lactating piglets affects the caecal microbiota and metabolomic response after weaning.Scientific reports · 2021Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Porcine epidemic diarrhea (PED) is a devastating disease in livestock industry. Most of the previous studies related to the PED were focused on the pathology and etiology of porcine epidemic diarrhea virus (PEDV). A little was known regarding the status of gut microbiota after piglets infected by PEDV. In this study, aided by metagenome sequencing technology, gut microbiota profiles in feces of viral diarrhea (VD) and viral control (VC) piglets were investigated. The results showed that the abundance of four dominant phyla (Fusobacteria, Actinobacteria, Verrucomicrobia, and Proteobacteria) in feces was affected greatly by porcine epidemic diarrhea. Especially, the abundance of Fusobacteria was higher in VD piglets (36%) than in VC piglets (5%). On the contrary, the Verrucomicrobia was detected in lower distribution proportion in VD piglets (around 0%) than in VC piglets (20%). Furthermore, 25 genera were significantly different between VC and VD piglets at the genus level. Among the 25 genera, Leptotrichia belonging to Fusobacteria was remarkably lower in VC piglets than in VD piglets. Akkermansia belonging to Verrucomicrobia was higher in VC piglets than in VD piglets. Our findings implicated that the gut microbiota associated with PED significantly provided an insight into the pathology and physiology of PED.
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