ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2015
Nuclear image-guided left ventricular pacing lead navigation feasibility of a new technique.
Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- Image-guided left ventricular lead placement in cardiac resynchronization therapy: focused on image fusion methods.Journal of applied biomedicine · 2019Review
- A Review of Image-guided Approaches for Cardiac Resynchronisation Therapy.Arrhythmia & electrophysiology review · 2017Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCurrent techniques for left ventricular (LV) lead implantation in patients with ischemic cardiomyopathy (ICM) typically underutilize information which is important for optimal lead location, including LV mechanical activation pattern and scar location. We sought to develop a technique in which this information, contained in single-photon emission computed tomographic (SPECT) images, could be integrated as to guide the electrophysiologist during the implantation procedure.
methodsFive ICM patients underwent SPECT as well as multidetector cardiac computed tomographic (MDCT) imaging prior to the LV lead implantation procedure. Images were merged to create a "fusion" image, in which the SPECT data were projected onto the anatomically accurate MDCT epicardial surface. The fusion image was registered to the operative field using the coronary veins, apparent on the MDCT image, as a fiducial system. After registration, LV lead implantation was guided by the fusion image using a commercial catheter navigation system.
resultsSuccessful guidance was achieved in each patient, with minimal disturbance to standard workflow. Leads were implanted in late-activating, unscarred regions according to the fusion image, with locations corroborated by fluoroscopic and electrographic features. In regions where leads were contiguous to the phrenic nerve shown on the fusion image, pacing consistently demonstrated diaphragmatic stimulation.
conclusionsIn this technical report, the description and feasibility of a new technique for SPECT image-guided LV pacing lead navigation is demonstrated. Prospective study will be required to confirm image precision and registration/navigation accuracy, as well as to demonstrate value relative to standard implantation techniques.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.