Evidence map›Paper›PMID 26319021›Full record

ArticleBMC research notes2015

Preventing hepatocellular carcinoma in Egypt: results of a Pilot Health Education Intervention Study.

Doa'a A Saleh, Sania Amr, Irene A Jillson, Judy Huei-yu Wang, Nancy Crowell, Christopher A Loffredo

Registry-linked trialAbstract read
In one paragraph

Article in BMC research notes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04220151 (Epigenetic Changes in Hepatocellular Carcinoma Developed After Direct Acting Antiviral Therapy for Chronic Hepatitis C), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04220151 unknown statusnot on this mapstarted 2020, after this paper: background citation

Epigenetic Changes in Hepatocellular Carcinoma Developed After Direct Acting Antiviral Therapy for Chronic Hepatitis C

TypeobservationalSponsorAssiut UniversityRan2020 to 2021Enrolled100ConditionsHepatocellular CarcinomaArmsDNA methylation
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Hepatocellular Carcinoma (HCC) in Egypt: A comprehensive overview.Journal of the Egyptian National Cancer Institute · 2020
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Doa'a A SalehCairo University, Cairo, Egypt. doa_a_saleh@yahoo.com.
Sania AmrUniversity of Maryland, Baltimore, MD, USA. samr@epi.umaryland.edu.
Irene A JillsonDepartment of Oncology, Georgetown University, 3970 Reservoir Rd, Washington DC, 20057, USA. iaj@georgetown.edu.
Judy Huei-yu WangDepartment of Oncology, Georgetown University, 3970 Reservoir Rd, Washington DC, 20057, USA. jw235@georgetown.edu.
Nancy CrowellDepartment of Oncology, Georgetown University, 3970 Reservoir Rd, Washington DC, 20057, USA. nancy.crowell1321@gmail.com.
Christopher A LoffredoDepartment of Oncology, Georgetown University, 3970 Reservoir Rd, Washington DC, 20057, USA. cal9@georgetown.edu.

Funding

MALIGNANT COMPLICATIONS OF CHRONIC HEPATITIS C VIRUSR01CA085888 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI LOFFREDO, CHRISTOPHER A · 1999 to 2009
$3.1M
NCI NIH HHS R01 CA085888NCI NIH HHS R01CA85888
6 · The paper itself

Abstract

backgroundHepatocellular carcinoma (HCC), one of the most fatal malignancies, is particularly prevalent in Egypt, where we previously found deficiencies in knowledge concerning HCC and its risk factors. Hepatitis B and C viral infections are highly prevalent in Egypt, pesticides are very commonly used, and diets are often contaminated by aflatoxin, especially in rural areas.

methodsWe conducted a study to pilot test a health education intervention addressing HCC, its risk factors, and its main modes of prevention. It included four health education modules: HCC, hepatitis viruses, pesticides and aflatoxin. We used a pre- and post-intervention set of questionnaires to assess knowledge gained by the participants.

resultsA total of 25 participants from a village in the Nile Delta area attended the health education session and completed the questionnaires. The education intervention significantly increased the participants' knowledge on HCC and its risk factors, particularly regarding the use of pesticides at home and aflatoxin contaminated foods (both p < 0.05). Overall, there was a 12% increase in the number of participants who believed that HCC could be prevented, and they reported their intention to practice prevention for HCC risk factors.

conclusionsWe found that the education intervention we pilot tested was feasible and proved effective in increasing participants' knowledge. Future efforts should focus on implementing targeted education programs in high-risk populations in Egypt.

Indexed as

AdultCarcinoma, HepatocellularEgyptFemaleHealth EducationHumansLiver NeoplasmsMaleMiddle AgedPilot ProjectsRisk FactorsYoung Adult

Identifiers

PMID26319021
PMCPMC4553015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.