Evidence map›Paper›PMID 26318524›Full record

ArticleNeuroImage2016

White matter abnormalities and impaired attention abilities in children born very preterm.

Andrea L Murray, Deanne K Thompson, Leona Pascoe, Alexander Leemans, Terrie E Inder, Lex W Doyle, Jacqueline F I Anderson, Peter J Anderson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
8.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 64 citations in OpenAlex.

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  18. Advances in functional and diffusion neuroimaging research into the long-term consequences of very preterm birth.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Review
  19. Article
  20. Paeoniflorin treatment regulates TLR4/NF-κB signaling, reduces cerebral oxidative stress and improves white matter integrity in neonatal hypoxic brain injury.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Andrea L MurrayVictorian Infant Brain Studies, Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Australia; Melbourne School of Psychological Sciences, The University of Melbourne, Melbourne, Australia.
Deanne K ThompsonVictorian Infant Brain Studies, Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Australia; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, Australia; Department of Paediatrics, The University of Melbourne, Royal Children's Hospital, Melbourne, Australia.
Leona PascoeVictorian Infant Brain Studies, Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Australia.
Alexander LeemansImage Sciences Institute, University Medical Center, Utrecht, The Netherlands.
Terrie E InderVictorian Infant Brain Studies, Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Australia; Department of Pediatric Newborn Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Lex W DoyleVictorian Infant Brain Studies, Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Australia; Research Office, The Royal Women's Hospital, Grattan Street, Melbourne, Australia; Department of Obstetrics & Gynaecology, The University of Melbourne, Royal Women's Hospital, Melbourne, Australia.
Jacqueline F I AndersonMelbourne School of Psychological Sciences, The University of Melbourne, Melbourne, Australia; Department of Psychology, The Alfred, Alfred Health, Melbourne, Australia.
Peter J AndersonVictorian Infant Brain Studies, Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Australia; Department of Paediatrics, The University of Melbourne, Royal Children's Hospital, Melbourne, Australia. Electronic address: peter.anderson@mcri.edu.au.
Murdoch Children's Research Institute · AUUniversity of Melbourne · AUAlfred Health · AURoyal Children's Hospital · AUUniversity Medical Center Utrecht · NL

Funding

Neurobehavioral Impairments in Preterm Children - A Longitudinal MR StudyR01HD058056 · NICHD · WASHINGTON UNIVERSITY · PI INDER, TERRIE E · 2008 to 2011
$1.9M
NICHD NIH HHS HD058056NICHD NIH HHS R01 HD058056
6 · The paper itself

Abstract

While attention impairments are commonly observed in very preterm (<32weeks' gestational age) children, neuroanatomical correlates of these difficulties are unclear. We aimed to determine whether the microstructural organization of key white matter tracts thought to be involved in attention (cingulum bundle, superior longitudinal fasciculi, reticular activating system, and corpus callosum) were altered in very preterm children compared with term-born controls. We also aimed to determine whether alterations in microstructural organization of these tracts were associated with attention functioning in very preterm children. One hundred and forty-nine very preterm children and 36 term-born controls underwent neuroimaging and assessment of their attention abilities at 7years. Constrained spherical deconvolution and probabilistic tractography was used to identify the key white matter tracts. Altered microstructural organization and reduced tract volume within reticular activating system and corpus callosum were found in the very preterm group compared with the control group. Diffusion and volume changes in the cingulum bundle, superior longitudinal fasciculi, reticular activating system, and corpus callosum were related to variations in attention functioning in the very preterm children. These findings emphasize that white matter tract integrity is associated with later attentional abilities in very preterm children.

Indexed as

AttentionBrainChildDiffusion Magnetic Resonance ImagingFemaleGestational AgeHumansInfant, Extremely PrematureInfant, NewbornMaleNeuropsychological TestsWhite MatterAttentionDiffusion-weighted imagingMagnetic resonance imagingVery pretermWhite matter injury

Identifiers

PMID26318524
PMCPMC4791057
OpenAlexW1464398625

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.