Evidence map›Paper›PMID 26317627›Full record

ArticlePloS one2015

Atrial Fibrillation and Colonic Neoplasia in African Americans.

Mehdi Nouraie, Vandana Kansal, Cassius Belfonte, Mohammad Ghazvini, Tahmineh Haidari, Anahita Shahnazi, Hassan Brim, Elsayed Z Soliman, Hassan Ashktorab

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Mehdi NouraieCancer Research Center, and Department of Medicine, Howard University College of Medicine, Washington, District of Columbia, United States of America.
Vandana KansalCancer Research Center, and Department of Medicine, Howard University College of Medicine, Washington, District of Columbia, United States of America.
Cassius BelfonteDepartment of Medicine, Division of Cardiology, Howard University College of Medicine, Washington, District of Columbia, United States of America.
Mohammad GhazviniDepartment of Medicine, Division of Cardiology, Howard University College of Medicine, Washington, District of Columbia, United States of America.
Tahmineh HaidariCancer Research Center, and Department of Medicine, Howard University College of Medicine, Washington, District of Columbia, United States of America.
Anahita ShahnaziCancer Research Center, and Department of Medicine, Howard University College of Medicine, Washington, District of Columbia, United States of America.
Hassan BrimCancer Research Center, and Department of Pathology, Howard University College of Medicine, Washington, District of Columbia, United States of America.
Elsayed Z SolimanEpidemiological Cardiology Research Center, Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston Salem, North Carolina, United States of America; Department of Internal Medicine-Cardiology, Wake Forest School of Medicine, Winston Salem, North Carolina, United States of America.
Hassan AshktorabCancer Research Center, and Department of Medicine, Howard University College of Medicine, Washington, District of Columbia, United States of America.
Cancer Research Center · USHoward University · USWake Forest University · US

Funding

PROTEOMICS CORE FACILITYG12MD007597 · NIMHD · HOWARD UNIVERSITY · PI SOUTHERLAND, WILLIAM M. · 2012 to 2018
$14.8M
NIMHD NIH HHS G12 MD007597NIMHD NIH HHS G12MD007597
6 · The paper itself

Abstract

backgroundColorectal cancer (CRC) and atrial fibrillation/flutter (AF) share several risk factors including increasing age and obesity. However, the association between CRC and AF has not been thoroughly examined, especially in African Americans. In this study we aimed to assess the prevalence of AF and its risk factors in colorectal neoplasia in an African American.

methodsWe reviewed records of 527 African American patients diagnosed with CRC and 1008 patients diagnosed with benign colonic lesions at Howard University Hospital from January 2000 to December 2012. A control group of 731 hospitalized patients without any cancer or colonic lesion were randomly selected from the same time and age range, excluding patients who had diagnosis of both CRC and/or adenoma. The presence or absence of AF was based upon ICD-9 code documentation. The prevalence of AF in these three groups was compared by multivariate logistic regression.

resultsThe prevalence of AF was highest among CRC patients (10%) followed by adenoma patients (7.2%) then the control group (5.4%, P for trend = 0.002). In the three groups of participants, older age (P<0.008) and heart failure (P<0.001) were significantly associated with higher risk of AF. After adjusting for these risk factors, CRC (OR: 1.4(95%CI):0.9-2.2, P = 0.2) and adenoma (OR: 1.1(95%CI):0.7-1.6, P = 0.7) were not significantly associated AF compared to control group.

conclusionsAF is highly prevalent among CRC patients; 1 in 10 patients had AF in our study. The predictors of AF in CRC was similar to that in adenoma and other patients after adjustment for potential confounders suggesting that the increased AF risk in CRC is explained by higher prevalence of AF risk factors.

Indexed as

Black or African AmericanAgedAtrial FibrillationColonic NeoplasmsFemaleHumansMaleMiddle AgedOdds RatioPrevalenceRisk Factors

Identifiers

PMID26317627
PMCPMC4552839
OpenAlexW2260637391

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.