Evidence map›Paper›PMID 26317047›Full record

ArticleAdipocyte

Adipose depots differ in cellularity, adipokines produced, gene expression, and cell systems.

Michael V Dodson, Min Du, Songbo Wang, Werner G Bergen, Melinda Fernyhough-Culver, Urmila Basu, Sylvia P Poulos, Gary J Hausman

Abstract read
In one paragraph

Article in Adipocyte. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. International journal of molecular sciences · 2021
    Article
  10. Review
  11. Adipokines and Inflammation: Focus on Cardiovascular Diseases.International journal of molecular sciences · 2020
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael V DodsonDepartment of Animal Sciences; Washington State University ; Pullman, WA USA.
Min DuDepartment of Animal Sciences; Washington State University ; Pullman, WA USA.
Songbo WangDepartment of Animal Sciences; Washington State University ; Pullman, WA USA ; College of Animal Science; South China Agricultural University ; Guangzhou, PR China.
Werner G BergenProgram in Cellular and Molecular Biosciences/Department of Animal Sciences; Auburn University ; Auburn, AL USA.
Melinda Fernyhough-CulverAbitec Corporation ; Columbus, OH USA.
Urmila BasuUniversity of Alberta ; Edmonton, AB Canada.
Sylvia P PoulosAkeso Health LLC ; Decatur, GA USA.
Gary J HausmanDepartment of Animal and Dairy Science; University of Georgia ; Athens, GA USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The race to manage the health concerns related to excess fat deposition has spawned a proliferation of clinical and basic research efforts to understand variables including dietary uptake, metabolism, and lipid deposition by adipocytes. A full appreciation of these variables must also include a depot-specific understanding of content and location in order to elucidate mechanisms governing cellular development and regulation of fat deposition. Because adipose tissue depots contain various cell types, differences in the cellularity among and within adipose depots are presently being documented to ascertain functional differences. This has led to the possibility of there being, within any one adipose depot, cellular distinctions that essentially result in adipose depots within depots. The papers comprising this issue will underscore numerous differences in cellularity (development, histogenesis, growth, metabolic function, regulation) of different adipose depots. Such information is useful in deciphering adipose depot involvement both in normal physiology and in pathology. Obesity, diabetes, metabolic syndrome, carcass composition of meat animals, performance of elite athletes, physiology/pathophysiology of aging, and numerous other diseases might be altered with a greater understanding of adipose depots and the cells that comprise them-including stem cells-during initial development and subsequent periods of normal/abnormal growth into senescence. Once thought to be dormant and innocuous, the adipocyte is emerging as a dynamic and influential cell and research will continue to identify complex physiologic regulation of processes involved in adipose depot physiology.

Indexed as

adipocyte gene expressionadipokineadipose depotsadipose lineage cellcellularity

Identifiers

PMID26317047
PMCPMC4550680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.