Evidence map›Paper›PMID 26316963›Full record

ArticleJournal of sexually transmitted diseases2013

The Impact of Integration of Rapid Syphilis Testing during Routine Antenatal Services in Rural Kenya.

Eleanor Fleming, Jared Oremo, Katherine O'Connor, Aloyce Odhiambo, Tun Ye, Simon Oswago, Clement Zeh, Robert Quick, Mary L Kamb

Abstract read
In one paragraph

Article in Journal of sexually transmitted diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Introduction of rapid syphilis testing in antenatal care: A systematic review of the impact on HIV and syphilis testing uptake and coverage.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2015
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  17. Assessment of the impact of rapid syphilis tests on syphilis screening and treatment of pregnant women in Zambia.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eleanor FlemingCenters for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Office of the Director, Office of Health Equity, 1600 Clifton Road Mailstop E07, Atlanta, GA 30333, USA ; Division of Applied Sciences, Epidemic Intelligence Service, Centers for Disease Control and Prevention, Scientific Education and Professional Development Program Office, Atlanta, GA 30333, USA.ORCID 0000-0003-4415-5410
Jared OremoSafe Water and AIDS Project, Kisumu 40100, Kenya.ORCID 0000-0002-1787-9037
Katherine O'ConnorDivision of Applied Sciences, Epidemic Intelligence Service, Centers for Disease Control and Prevention, Scientific Education and Professional Development Program Office, Atlanta, GA 30333, USA ; Division of Foodborne, Waterborne and Environmental Diseases, Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases, Atlanta, GA 30333, USA.
Aloyce OdhiamboSafe Water and AIDS Project, Kisumu 40100, Kenya.
Tun YeCenters for Disease Control and Prevention, Center for Global Health, Office of the Director, Atlanta, GA 30333, USA.
Simon OswagoKenya Medical Research Institute (KEMRI), Kisian 40100, Kenya.ORCID 0000-0002-7474-0357
Clement ZehKenya Medical Research Institute (KEMRI), Kisian 40100, Kenya.
Robert QuickDivision of Foodborne, Waterborne and Environmental Diseases, Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases, Atlanta, GA 30333, USA.ORCID 0000-0002-1861-0734
Mary L KambCenters for Disease Control and Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Office of the Director, Office of Health Equity, 1600 Clifton Road Mailstop E07, Atlanta, GA 30333, USA.ORCID 0000-0002-0584-2771

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated the integration of rapid syphilis tests (RSTs) and penicillin treatment kits into routine antenatal clinic (ANC) services in two rural districts in Nyanza Province, Kenya. In February 2011, nurses from 25 clinics were trained in using RSTs and documenting test results and treatment. During March 2011-February 2012, free RSTs and treatment kits were provided to clinics for use during ANC visits. We analyzed ANC registry data from eight clinics during the 12-month periods before and during RST program implementation and compared syphilis testing, diagnosis, and treatment during the two periods. Syphilis testing at first ANC visit increased from 18% (279 of 1,586 attendees) before the intervention to 70% (1,123 of 1,614 attendees) during the intervention (P < 0.001); 35 women (3%) tested positive during the intervention period compared with 1 (<1%) before (P < 0.001). Syphilis treatment was not recorded according to training recommendations; seven clinics identified 28 RST-positive women and recorded 34 treatment kits as used. Individual-level data from three high-volume clinics supported that the intervention did not negatively affect HIV test uptake. Integrating RSTs into rural ANC services increased syphilis testing and detection. Record keeping on treatment of syphilis in RST-positive women remains challenging.

Identifiers

PMID26316963
PMCPMC4437431

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.