Evidence map›Paper›PMID 26316799›Full record

ArticleInternational journal of general medicine2015

Health behaviors and quality of life predictors for risk of hospitalization in an electronic health record-linked biobank.

Paul Y Takahashi, Euijung Ryu, Janet E Olson, Erin M Winkler, Matthew A Hathcock, Ruchi Gupta, Jeff A Sloan, Jyotishman Pathak, Suzette J Bielinski, James R Cerhan

Abstract read
In one paragraph

Article in International journal of general medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Synth-SBDH: A Synthetic Dataset of Social and Behavioral Determinants of Health for Clinical Text.Proceedings of the Conference on Empirical Methods in Natural Language Processing. Conference on Empirical Methods in Natural Language Processing · 2025
    Article
  3. Article
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  6. MIMIC-SBDH: A Dataset for Social and Behavioral Determinants of Health.Proceedings of machine learning research · 2021
    Article
  7. Observational
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Paul Y TakahashiDivision of Primary Care Internal Medicine, Mayo Clinic, Rochester, MN, USA ; Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Euijung RyuDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Janet E OlsonDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Erin M WinklerCenter for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.
Matthew A HathcockDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Ruchi GuptaDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Jeff A SloanDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Jyotishman PathakDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Suzette J BielinskiDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
James R CerhanDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.

Funding

National Infrastructure for Standardized and Portable EHR Phenotyping AlgorithmsR01GM105688 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI LUO, YUAN, PATHAK, JYOTISHMAN · 2013 to 2020
$5.7M
NIGMS NIH HHS R01 GM105688
6 · The paper itself

Abstract

backgroundHospital risk stratification models using electronic health records (EHRs) often use age and comorbid health burden. Our primary aim was to determine if quality of life or health behaviors captured in an EHR-linked biobank can predict future risk of hospitalization.

methodsParticipants in the Mayo Clinic Biobank completed self-administered questionnaires at enrollment that included quality of life and health behaviors. Participants enrolled as of December 31, 2010 were followed for one year to ascertain hospitalization. Data on comorbidities and hospitalization were derived from the Mayo Clinic EHR. Hazard ratios (HR) and 95% confidence interval (CI) were used, adjusted for age and sex. We used gradient boosting machines models to integrate multiple factors. Different models were compared using C-statistic.

resultsOf the 8,927 eligible Mayo Clinic Biobank participants, 834 (9.3%) were hospitalized. Self-perceived health status and alcohol use had the strongest associations with risk of hospitalization. Compared to participants with excellent self-perceived health, those reporting poor/fair health had higher risk of hospitalization (HR =3.66, 95% CI 2.74-4.88). Alcohol use was inversely associated with hospitalization (HR =0.57 95% CI 0.45-0.72). The gradient boosting machines model estimated self-perceived health as the most influential factor (relative influence =16%). The predictive ability of the model based on comorbidities was slightly higher than the one based on the self-perceived health (C-statistic =0.67 vs 0.65).

conclusionThis study demonstrates that self-perceived health may be an important piece of information to add to the EHR. It may be another method to determine hospitalization risk.

Indexed as

agingalcoholEHRhealth behaviorhospitalizationmultiple chronic conditionsquality of life

Identifiers

PMID26316799
PMCPMC4540136

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.