Evidence map›Paper›PMID 26316736›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2015

Discrepancies between modified Medical Research Council dyspnea score and COPD assessment test score in patients with COPD.

Chin Kook Rhee, Jin Woo Kim, Yong Il Hwang, Jin Hwa Lee, Ki-Suck Jung, Myung Goo Lee, Kwang Ha Yoo, Sang Haak Lee, Kyeong-Cheol Shin, Hyoung Kyu Yoon

Abstract readComparative StudyMulticenter Study
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  14. The clinical efficacy of AG NPP709 (SynaturaJournal of thoracic disease · 2020
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  15. Variation in Assignment of the COPD Patients into a GOLD Group According to Symptoms Severity.International journal of chronic obstructive pulmonary disease · 2020
    Observational
  16. Article
  17. Observational
  18. Factors associated with exacerbation in mild- to-moderate COPD patients.International journal of chronic obstructive pulmonary disease · 2016
    Article
  19. COPD assessment test score and serum C-reactive protein levels in stable COPD patients.International journal of chronic obstructive pulmonary disease · 2016
    Observational
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Chin Kook RheeDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Jin Woo KimDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Uijeongbu St Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Republic of Korea.
Yong Il HwangDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Hallym University College of Medicine, Anyang, Republic of Korea.
Jin Hwa LeeDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, School of Medicine, Ewha Womans University, Seoul, Republic of Korea.
Ki-Suck JungDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Hallym University College of Medicine, Anyang, Republic of Korea.
Myung Goo LeeDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Republic of Korea.
Kwang Ha YooDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Republic of Korea.
Sang Haak LeeDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, St Paul's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Kyeong-Cheol ShinRegional Center for Respiratory Disease, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, Republic of Korea.
Hyoung Kyu YoonDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yeouido St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveAccording to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines, either a modified Medical Research Council (mMRC) dyspnea score of ≥2 or a chronic obstructive pulmonary disease (COPD) assessment test (CAT) score of ≥10 is considered to represent COPD patients who are more symptomatic. We aimed to identify the ideal CAT score that exhibits minimal discrepancy with the mMRC score.

methodsA receiver operating characteristic curve of the CAT score was generated for an mMRC scores of 1 and 2. A concordance analysis was applied to quantify the association between the frequencies of patients categorized into GOLD groups A-D using symptom cutoff points. A κ-coefficient was calculated.

resultsFor an mMRC score of 2, a CAT score of 15 showed the maximum value of Youden's index with a sensitivity and specificity of 0.70 and 0.66, respectively (area under the receiver operating characteristic curve [AUC] 0.74; 95% confidence interval [CI], 0.70-0.77). For an mMRC score of 1, a CAT score of 10 showed the maximum value of Youden's index with a sensitivity and specificity of 0.77 and 0.65, respectively (AUC 0.77; 95% CI, 0.72-0.83). The κ value for concordance was highest between an mMRC score of 1 and a CAT score of 10 (0.66), followed by an mMRC score of 2 and a CAT score of 15 (0.56), an mMRC score of 2 and a CAT score of 10 (0.47), and an mMRC score of 1 and a CAT score of 15 (0.43).

conclusionA CAT score of 10 was most concordant with an mMRC score of 1 when classifying patients with COPD into GOLD groups A-D. However, a discrepancy remains between the CAT and mMRC scoring systems.

Indexed as

Surveys and QuestionnairesAgedArea Under CurveCross-Sectional StudiesDyspneaFemaleForced Expiratory VolumeHumansLungMaleMiddle AgedPredictive Value of TestsPulmonary Disease, Chronic ObstructiveReproducibility of ResultsRepublic of KoreaRisk FactorsCATconcordanceCOPDdiscrepancymMRC

Identifiers

PMID26316736
PMCPMC4541543

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.