Evidence map›Paper›PMID 26316729›Full record

Trial reportClinical interventions in aging2015

Does multicomponent physical exercise with simultaneous cognitive training boost cognitive performance in older adults? A 6-month randomized controlled trial with a 1-year follow-up.

Patrick Eggenberger, Vera Schumacher, Marius Angst, Nathan Theill, Eling D de Bruin

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinical interventions in aging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05991011 (Moving While Thinking or Thinking While Moving? Comparison of the Cognitive, Dual-task and Physical Effects of 6 Programs With Older Adults), which is not on this map. Cited by 115 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05991011 nacompletednot on this mapstarted 2023, after this paper: background citation

Moving While Thinking or Thinking While Moving? Comparison of the Cognitive, Dual-task and Physical Effects of 6 Programs With Older Adults

TypeinterventionalSponsorAlexandra PerrotRan2023 to 2025Enrolled174ConditionsPhysical Fitness, Cognitive FunctionArmsImmersive and Interactive Wall Exergames, Complex Cognitive and Motor Activities program, exergames program, video games program, Bike
3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 12 syntheses or guidelines pooled it.

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55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Patrick EggenbergerInstitute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, ETH Zurich, Switzerland.
Vera SchumacherDepartment of Gerontopsychology and Gerontology, University of Zurich, Zurich, Switzerland ; University Research Priority Program "Dynamics of Healthy Aging", University of Zurich, Zurich, Switzerland.
Marius AngstInstitute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, ETH Zurich, Switzerland.
Nathan TheillDivision of Psychiatry Research, University of Zurich, Schlieren, Switzerland ; Center for Gerontology, University of Zurich, Zurich, Switzerland.
Eling D de BruinInstitute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, ETH Zurich, Switzerland ; CAPHRI School for Public Health and Primary Care, Department of Epidemiology, Maastricht University, Maastricht, the Netherlands ; Centre for Evidence Based Physiotherapy, Maastricht University, Maastricht, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCognitive impairment is a health problem that concerns almost every second elderly person. Physical and cognitive training have differential positive effects on cognition, but have been rarely applied in combination. This study evaluates synergistic effects of multicomponent physical exercise complemented with novel simultaneous cognitive training on cognition in older adults. We hypothesized that simultaneous cognitive-physical components would add training specific cognitive benefits compared to exclusively physical training.

methodsSeniors, older than 70 years, without cognitive impairment, were randomly assigned to either: 1) virtual reality video game dancing (DANCE), 2) treadmill walking with simultaneous verbal memory training (MEMORY), or 3) treadmill walking (PHYS). Each program was complemented with strength and balance exercises. Two 1-hour training sessions per week over 6 months were applied. Cognitive performance was assessed at baseline, after 3 and 6 months, and at 1-year follow-up. Multiple regression analyses with planned comparisons were calculated.

resultsEighty-nine participants were randomized to the three groups initially, 71 completed the training, while 47 were available at 1-year follow-up. Advantages of the simultaneous cognitive-physical programs were found in two dimensions of executive function. "Shifting attention" showed a time×intervention interaction in favor of DANCE/MEMORY versus PHYS (F[2, 68] =1.95, trend P=0.075, r=0.17); and "working memory" showed a time×intervention interaction in favor of DANCE versus MEMORY (F[1, 136] =2.71, trend P=0.051, R (2)=0.006). Performance improvements in executive functions, long-term visual memory (episodic memory), and processing speed were maintained at follow-up in all groups.

conclusionParticular executive functions benefit from simultaneous cognitive-physical training compared to exclusively physical multicomponent training. Cognitive-physical training programs may counteract widespread cognitive impairments in the elderly.

Indexed as

Video GamesAgedAged, 80 and overCognitionDancingExecutive FunctionExercise TherapyFemaleFollow-Up StudiesHumansLearningMaleNeuropsychological TestsPostural BalanceWalkingcognitive impairmentdanceelderlyexecutive functiontransfervideo game

Identifiers

PMID26316729
PMCPMC4544626

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.