ArticleJournal of applied physiology (Bethesda, Md. : 1985)2015
Explained variance in the thermoregulatory responses to exercise: the independent roles of biophysical and fitness/fatness-related factors.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed.
- Caffeine ingestion compromises thermoregulation and does not improve cycling time to exhaustion in the heat amongst males.European journal of applied physiology · 2024Trial
- Interaction of Exercise Intensity and Simulated Burn Injury Size on Thermoregulation.Medicine and science in sports and exercise · 2021Trial
- Thermophysiological and perceptual responses to exercise heat stress in people with cystic fibrosis on Elexacaftor/Tezacaftor/Ivacaftor.Experimental physiology · 2026Article
- Macro- and microcirculatory factors affecting foot temperature change during walking.Experimental physiology · 2026Article
- Influence of age and biological sex on sweating in children exercising in warm and hot environments with comparison to adults.The Journal of physiology · 2026Article
- The maturation of regional sweating patterns from childhood to young adulthood in females.Experimental physiology · 2026Article
- Can evaporative cooling attenuate physiological and perceptual responses during exercise in Hot/Dry and Warm/Humid environments?Industrial health · 2026Article
- Physiological response to exercise in the heat: Implications for risk mitigation and adaptation.Temperature (Austin, Tex.) · 2025Article
- The effect of female breast surface area on heat-activated sweat gland density and output.Experimental physiology · 2024Article
- Adaptive fabric with emissivity regulation for thermal management of humans.Nanophotonics (Berlin, Germany) · 2024Article
- Biophysical, thermo-physiological and perceptual determinants of cool-seeking behaviour during exercise in younger and older women.Experimental physiology · 2024Article
- Evidence of a Causal Relationship Between Body Mass Index and Immune-Mediated and Inflammatory Skin Diseases and Biomarkers: A Mendelian Randomization Study.Clinical, cosmetic and investigational dermatology · 2024Article
- A century of exercise physiology: concepts that ignited the study of human thermoregulation. Part 2: physiological measurements.European journal of applied physiology · 2023Review
- To the extreme! How biological anthropology can inform exercise physiology in extreme environments.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 2023Review
- Beating the heat: military training and operations in the era of global warming.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Review
- Combining hypoxia with thermal stimuli in humans: physiological responses and potential sex differences.American journal of physiology. Regulatory, integrative and comparative physiology · 2023Review
- Relatively minor influence of individual characteristics on critical wet-bulb globe temperature (WBGT) limits during light activity in young adults (PSU HEAT Project).Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
- Quantifying the impact of heat on human physical work capacity; part IV: interactions between work duration and heat stress severity.International journal of biometeorology · 2022Article
- Human temperature regulation under heat stress in health, disease, and injury.Physiological reviews · 2022Review
- Classic and exertional heatstroke.Nature reviews. Disease primers · 2022Review
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
Individual variation in the thermoregulatory responses to exercise is notoriously large. Although aerobic fitness (V̇o2 max) and body fatness are traditionally considered important predictors of individual core temperature and sweating responses, recent evidence indicates potentially important and independent roles for biophysical factors. Using stepwise regression, we examined the proportion of individual variability in rectal temperature changes (ΔTre), whole body sweat loss (WBSL), and steady-state local sweat rate (LSRss) independently described by 1) biophysical factors associated with metabolic heat production (Hprod) and evaporative heat balance requirements (Ereq) relative to body size and 2) factors independently related to V̇o2 max and body fatness. In a total of 69 trials, 28 males of wide-ranging morphological traits and V̇o2 max values cycled at workloads corresponding to a range of absolute Hprod (410-898 W) and relative intensities (32.2-82.0% V̇o2 max) for 60 min in 24.8 ± 0.7°C and 33.4 ± 12.2% relative humidity. Hprod (in W/kg total body mass) alone described ∼50% of the variability in ΔTre (adjusted to r(2) = 0.496; P < 0.001), whereas surface area-to-mass ratio and body fat percentage (BF%) explained an additional 4.3 and 2.3% of variability, respectively. For WBSL, Ereq (in W) alone explained ∼71% of variance (adjusted to r(2) = 0.713, P < 0.001), and the inclusion of BF% explained an additional 1.3%. Similarly, Ereq (in W/m(2)) correlated significantly with LSRss (adjusted to r(2) = 0.603, P < 0.001), whereas %V̇o2 max described an additional ∼4% of total variance. In conclusion, biophysical parameters related to Hprod, Ereq, and body size explain 54-71% of the individual variability in ΔTre, WBSL, and LSRss, and only 1-4% of additional variance is explained by factors related to fitness or fatness.
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